Three-dimensional bioprinting of anatomically realistic tissue constructs for disease modeling and drug testing

NI Moldovan - Tissue Engineering Part C: Methods, 2021 - liebertpub.com
Three-dimensional (3D) bioprinting is an emerging tissue engineering technology, already
with several remarkable accomplishments and with more promises to fulfill. Besides the …

A novel murine model expressing a chimeric mSCARB2/hSCARB2 receptor is highly susceptible to oral infection with clinical isolates of enterovirus 71

CH Yang, CT Liang, ST Jiang, KH Chen… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) infection is generally associated with hand-foot-and-
mouth disease (HFMD) and may cause severe neurological disorders and even death. An …

In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

N de Buhr, A Martens, M Meurer, MC Bonilla… - BMC neuroscience, 2021 - Springer
During infection and inflammation, a reduced oxygen level clearly affects cellular functions.
Oxygen levels during CNS infections are unknown. Here we established and evaluated an …

Acute Rift Valley fever virus infection induces inflammatory cytokines and cell death in ex vivo rat brain slice culture

KA Connors, ZD Frey, MJ Demers… - Journal of General …, 2024 - microbiologyresearch.org
Rift Valley fever virus (RVFV) is an emerging arboviral disease with pandemic potential.
While infection is often self-limiting, a subset of individuals may develop late-onset …

A novel method for oxygen glucose deprivation model in organotypic spinal cord slices

JJ Liu, XY Ding, L Xiang, F Zhao, SL Huang - Brain research bulletin, 2017 - Elsevier
This study aimed to establish a model to closely mimic spinal cord hypoxic-ischemic injury
with high production and high reproducibility. Fourteen-day cultured organotypic spinal cord …

A novel method of organotypic spinal cord slice culture in rats

JJ Liu, YJ Huang, L Xiang, F Zhao, SL Huang - Neuroreport, 2017 - journals.lww.com
This study was undertaken to establish a method for the culture of organotypic spinal cord
slices. A long-term organotypic spinal cord slice culture was conducted from postnatal rats …

Characterization of neural infection by Oropouche orthobunyavirus

KA Connors, MR Pedlow, ZD Frey, JJ McGaughey… - bioRxiv, 2024 - biorxiv.org
Oropouche fever is a re-emerging global viral threat caused by infection with Oropouche
orthobunyavirus (OROV). While disease is generally self-limiting, historical and recent …

Investigation of inflammation-promoted gadolinium retention within the central nervous system in the EAE mouse model and ex vivo

LC Anderhalten - 2024 - refubium.fu-berlin.de
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that is characterized by autoimmune-driven inflammation, resulting in myelin …

Development and application of optical microscopy tools for the study of axon guidance

L Wunderlich - 2024 - repository.cam.ac.uk
During their development, neurons extend axons towards their target cells, where they
branch to establish connections. The navigation of axons relies on the presence of chemical …

Untersuchung neurotroper Determinanten des Masernvirus an Gehirnschnittkulturen von Lewis Ratten

J Busch - 2021 - ul.qucosa.de
Abstract (DE) Für die Bekämpfung sowie Behandlung einer Krankheit ist das vollständige
Verständnis ihrer Pathogenese eminent. Die Masern werden durch das Masernvirus (MV) …