I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

The field of chronic rhinosinusitis (CRS) is constantly evolving. In the past 10 years, key
advancements in basic and translational research as well as clinical studies have improved …

Importance Olfactory dysfunction (OD) is an increasingly common and morbid condition,
especially given the ongoing COVID-19 pandemic. Thus, the ability to reproducibly measure …

Objective To evaluate the efficacy and safety of intranasal theophylline saline irrigation on
olfactory recovery in patients with post-viral olfactory dysfunction (PVOD). Methods Between …

Chronic rhinosinusitis (CRS) is an inflammatory condition of the paranasal sinuses defined
by classic symptoms, imaging findings, or endoscopic findings. There are a growing number …

Chronic rhinosinusitis (CRS) is a highly prevalent condition. CRS is usually managed with
intranasal corticosteroids, useful both before as well as after endoscopic sinus surgery …

Objective To analyze published reports on the efficacy and safety of CSI in CRS and
evaluate the clinical implications of current gaps in evidence. Corticosteroid irrigation (CSI) …

Nasal irrigation (NI) for the local treatment of chronic rhinosinusitis (CRS) has some
specificity due to the deep anatomical site of the sinuses. The purpose of this review is to …

Objective This study aims to compare the potential sinus distribution between high‐volume
nasal irrigation and nasal spray in chronic rhinosinusitis (CRS) patients who have not …

Background Evidence supporting topical steroids for the treatment of chronic rhinosinusitis
without nasal polyposis (CRSsNP) is unclear. Recent trials describe alternative topical …