The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

Discarded human donor organs have been shown to provide decellularized extracellular
matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell …

With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

The availability of an autologous transplantable auxiliary liver would dramatically affect the
treatment of liver disease. Assembly and function in vivo of a bioengineered human liver …

Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

The term “liver tissue engineering” summarizes one of the ultimate goals of modern
biotechnology: the possibility of reproducing in total or in part the functions of the liver in …

The liver, the largest organ in the human body, is a multi-functional organ with diverse
metabolic activities that plays a critical role in maintaining the body and sustaining life …

With the increasing number of accepted candidates on waiting lists worldwide, there is an
urgent need to expand the number and the quality of donor livers. Dynamic preservation …