An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
Alopecia Areata (AA) is a common autoimmune disease characterized by non-scarring hair
loss ranging from patches on the scalp to complete hair loss involving the entire body …
loss ranging from patches on the scalp to complete hair loss involving the entire body …
Alopecia areata: a review of disease pathogenesis
Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …
psychological impact can be significant, leading to feelings of depression and social …
A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity
Virtual memory T (TVM) cells are a T cell subtype with a memory phenotype but no prior
exposure to foreign antigen. Although TVM cells have antiviral and antibacterial functions …
exposure to foreign antigen. Although TVM cells have antiviral and antibacterial functions …
Alopecia areata: animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies
One of the most common human autoimmune diseases, alopecia areata (AA), is
characterized by sudden, often persisting and psychologically devastating hair loss. Animal …
characterized by sudden, often persisting and psychologically devastating hair loss. Animal …
Alopecia areata: what's new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
T Dainichi, K Kabashima - Journal of dermatological science, 2017 - Elsevier
Alopecia areata (AA) is a common and stressful disorder that results in hair loss, and
resistant to treatment in some cases. Experimental and clinical evidence suggests that AA is …
resistant to treatment in some cases. Experimental and clinical evidence suggests that AA is …
Pathomechanisms of immune-mediated alopecia
The hair follicle (HF) is a complex mini-organ that constantly undergoes dynamic cycles of
growth and regression throughout life. While proper progression of the hair cycle requires …
growth and regression throughout life. While proper progression of the hair cycle requires …
[HTML][HTML] Identification of autoantigen epitopes in alopecia areata
EHC Wang, M Yu, T Breitkopf… - Journal of Investigative …, 2016 - Elsevier
Alopecia areata (AA) is believed to be a cell-mediated autoimmune hair loss disease. Both
CD4 and cytotoxic CD8 T cells (CTLs) are important for the onset and progression of AA …
CD4 and cytotoxic CD8 T cells (CTLs) are important for the onset and progression of AA …
Innovative strategies for the discovery of new drugs against alopecia areata: taking aim at the immune system
HW Guo, ZM Ye, SQ Chen… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction The autoimmune hair loss condition alopecia areata (AA) exacts a substantial
psychological and socioeconomic toll on patients. Biotechnology companies, dermatology …
psychological and socioeconomic toll on patients. Biotechnology companies, dermatology …
Selective expansion of tregs using the IL-2 cytokine antibody complex does not reverse established alopecia areata in C3H/HeJ mice
E Lee, M Kim, YJ Lee - Frontiers in Immunology, 2022 - frontiersin.org
Alopecia areata (AA) is an autoimmune disease mediated by NKG2D-expressing cytotoxic T
lymphocytes destroying hair follicles in the skin. It is one of the most common autoimmune …
lymphocytes destroying hair follicles in the skin. It is one of the most common autoimmune …
A “hair‐raising” history of alopecia areata
D Broadley, KJ McElwee - Experimental dermatology, 2020 - Wiley Online Library
A 3500‐year‐old papyrus from ancient Egypt provides a list of treatments for many diseases
including “bite hair loss,” most likely alopecia areata (AA). The treatment of AA remained …
including “bite hair loss,” most likely alopecia areata (AA). The treatment of AA remained …