The existence of the blood-brain barrier (BBB) restricts the entry of drugs from the circulation
into the central nervous system (CNS), which severely affects the treatment of neurological …

Adolescence is a period of increased risk taking, including increased alcohol and drug use.
Multiple clinical studies report a positive relationship between adolescent alcohol …

People with sickle cell disease (SCD) often experience chronic pain as well as
unpredictable episodes of acute pain, which significantly affects their quality of life and life …

Introduction: Cannabis is the most used illicit drug in the United States. With many states
passing legislation to permit its recreational use, there is concern that cannabis use among …

Cannabis use by adolescents is widespread, but its effects on the ovaries remain largely
unknown. Δ9-tetrahydrocannabinol (THC) exerts its pharmacological effects by activating …

Endocannabinoids are derived from dietary omega-3 and omega-6 fatty acids and play an
important role in regulation of inflammation, development, neurodegenerative diseases …

Given the increasing use of cannabis in the US, there is an urgent need to better understand
the drug's effects on central signaling mechanisms. Extracellular vesicles (EVs) have been …

Abstract MDMB‐4F‐BICA, also known as 4F‐MDMB‐BICA, is a new psychoactive substance
that emerged in 2020. It is often illegally added to electronic cigarette oil for inhalation …

Adolescence is a period of increased risk taking, including increased alcohol and drug use.
Multiple clinical studies report a positive relationship between adolescent alcohol …

Cannabis exposure during gestation evokes significant molecular modifications to
neurodevelopmental programs leading to neurophysiological and behavioral abnormalities …