Matrix metalloproteinases (MMPs) consist of a multigene family of zinc‐dependent
extracellular matrix (ECM) remodeling endopeptidases implicated in pathological …

Syndecans are a small family of four transmembrane proteoglycans in mammals. They have
similar structural organization, consisting of an N‐terminal ectodomain, single …

Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major
components of extracellular matrix playing key roles in its structural organization and cell …

The expression of proteoglycans (PGs), essential macromolecules of the tumor
microenvironment, is markedly altered during malignant transformation and tumor …

In hormone-dependent breast cancer, estrogen receptors are the principal signaling
molecules that regulate several cell functions either by the genomic pathway acting directly …

Abstract The 17β-estradiol (E2)/estrogen receptor alpha (ERα) signaling pathway is one of
the most important pathways in hormone-dependent breast cancer. E2 plays pivotal roles in …

SLC6A14, also known as ATB 0,+, is an amino acid transporter with unique characteristics. It
transports 18 of the 20 proteinogenic amino acids. However, this transporter is expressed …

High expression of estrogen receptor α (ER α) is associated with a poor prognosis that
correlates closely with cellular proliferation in breast cancer. However, the exact molecular …

Proteoglycans control numerous normal and pathological processes, among which are
morphogenesis, tissue repair, inflammation, vascularization and cancer metastasis. During …

In the human genome, miR‐451a, miR‐144‐5p (passenger strand), and miR‐144‐3p (guide
strand) reside in clustered microRNA (mi RNA) sequences located within the 17q11. 2 …