Regeneration and tumorigenesis share common molecular pathways, nevertheless the
outcome of regeneration is life, whereas tumorigenesis leads to death. Although the process …

Pluripotent stem cells (PSCs) are capable of unlimited self-renewal in culture and
differentiation into all functional cell types in the body, and thus hold great promise for …

The transcription factor p53 protects neurons from transformation and DNA damage through
the induction of cell‐cycle arrest, DNA repair and apoptosis in a range of in vitro and in vivo …

Transcription regulates axon outgrowth and regeneration. However, to date, no transcription
complexes have been shown to control axon outgrowth and regeneration by regulating axon …

Induced pluripotent stem cells (iPSCs) are mainly characterized by their unlimited
proliferation abilities and potential to develop into almost any cell type. The creation of this …

The tumor suppressor p53 controls a broad range of cellular responses. Induction of a
transient (cell cycle arrest) or a permanent (senescence) block of cell proliferation, or the …

P53 plays a key role in the cellular response to damage exposure and in preventing the
development of human cancers. Activation of p53 results in changes in the expression of a …

Ischemic stroke (IS) is a severe and sudden cerebrovascular event, associated with notably
high rates of mortality and morbidity. The process of apoptosis, a genetically orchestrated …

A novel dipeptidomimetic containing a cyclic threonine - Chemical Communications (RSC
Publishing) DOI:10.1039/B915220B Royal Society of Chemistry ViewáPDFáVersionPreviousáArticleNextáArticle …

The function of the tumor suppressor p53 as a sequence specific transcription factor
controlling the expression of numerous target genes is critical for the regulation of cellular …