The role of dectin-1 in health and disease

N Kalia, J Singh, M Kaur - Immunobiology, 2021 - Elsevier
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an
emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin …

[HTML][HTML] Pattern recognition: recent insights from Dectin-1

DM Reid, NAR Gow, GD Brown - Current opinion in immunology, 2009 - Elsevier
The β-glucan receptor Dectin-1 is an archetypical non-toll-like pattern recognition receptor
expressed predominantly by myeloid cells, which can induce its own intracellular signalling …

High mitochondrial respiration and glycolytic capacity represent a metabolic phenotype of human tolerogenic dendritic cells

F Malinarich, K Duan, RA Hamid, A Bijin… - The Journal of …, 2015 - journals.aai.org
Human dendritic cells (DCs) regulate the balance between immunity and tolerance through
selective activation by environmental and pathogen-derived triggers. To characterize the …

Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells

NA Barrett, A Maekawa, OM Rahman… - The Journal of …, 2009 - journals.aai.org
House dust mites are a significant source of airborne allergen worldwide, but there is little
understanding of how they so potently generate allergic inflammation. We found that extracts …

β‐Glucans and Dectin‐1

SV Tsoni, GD Brown - Annals of the New York Academy of …, 2008 - Wiley Online Library
β‐Glucans are naturally occurring carbohydrates that possess immune‐modulating
activities, but their mechanisms of action are largely unknown. Recent discoveries, however …

Dendritic cells and C‐type lectin receptors: coupling innate to adaptive immune responses

SJ Van Vliet, JJ García‐Vallejo… - Immunology and cell …, 2008 - Wiley Online Library
Dendritic cells (DCs) have an important function in the initiation and differentiation of
immune responses, linking innate information to tailored adaptive responses. Depending on …

Brewer's yeast polysaccharides—a review of their exquisite structural features and biomedical applications

R Bastos, PG Oliveira, VM Gaspar, JF Mano… - Carbohydrate …, 2022 - Elsevier
Recent advances on brewer's yeast cell wall polysaccharides have unraveled exquisite
structural features and diverse composition with (β1→ 3),(β1→ 6),(α1→ 4),(β 1→ 4)-mix …

Innate signaling by the C-type lectin DC-SIGN dictates immune responses

J Den Dunnen, SI Gringhuis… - Cancer Immunology …, 2009 - Springer
Effective immune responses depend on the recognition of pathogens by dendritic cells
(DCs) through pattern recognition receptors (PRRs). These receptors induce specific …

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

A Esteban, MW Popp, VK Vyas… - Proceedings of the …, 2011 - National Acad Sciences
Dectin-1, the major β-glucan receptor in leukocytes, triggers an effective immune response
upon fungal recognition. Here we use sortase-mediated transpeptidation, a technique that …

Syk‐coupled C‐type lectin receptors that mediate cellular activation via single tyrosine based activation motifs

AM Kerrigan, GD Brown - Immunological reviews, 2010 - Wiley Online Library
Different dendritic cell (DC) subsets have distinct specialized functions contributed in part by
their differential expression of pattern recognition receptors (PRRs). C‐type lectin receptors …