Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …

CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

The synaptic tagging and capture hypothesis of protein synthesis-dependent long-term
potentiation asserts that the induction of synaptic potentiation creates only the potential for a …

Calcium/calmodulin-stimulated protein kinase II (CaMKII) is a family of broad substrate
specificity serine (Ser)/threonine (Thr) protein kinases widely expressed in many tissues that …

Long-term potentiation (LTP) in the CA1 region of the hippocampus has been the primary
model by which to study the cellular and molecular basis of memory. Calcium/calmodulin …

Long-term potentiation (LTP) is arguably the most compelling cellular model for learning and
memory. While the mechanisms underlying the induction of LTP ('learning') are well …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

The Ca 2+/Calmodulin (CaM)-dependent protein kinase II (CaMKII) is activated by Ca
2+/CaM, but becomes partially autonomous (Ca 2+-independent) upon autophosphorylation …

Ceulemans, Hugo, and Mathieu Bollen. Functional Diversity of Protein Phosphatase-1, a
Cellular Economizer and Reset Button. Physiol Rev 84: 1–39, 2004; 10.1152/physrev …

Many protein kinases themselves are regulated by reversible phosphorylation. Upon cell
stimulation, specific kinases are transiently phosphorylated and activated. Several of these …