Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …
Effects of Everolimus in Modulating the Host Immune Responses against Mycobacterium tuberculosis Infection
A Raien, S Davis, M Zhang, D Zitser, M Lin, G Pitcher… - Cells, 2023 - mdpi.com
The phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin
(P13K/AKT/mTOR) pathway plays a key role in tuberculosis (TB) pathogenesis and infection …
(P13K/AKT/mTOR) pathway plays a key role in tuberculosis (TB) pathogenesis and infection …
The innate memory response of macrophages to Mycobacterium tuberculosis is shaped by the nature of the antigenic stimuli
Innate immune cells, such as macrophages, mount an immune response upon exposure to
antigens and pathogens. Emerging evidence shows that macrophages exposed to an …
antigens and pathogens. Emerging evidence shows that macrophages exposed to an …
Everolimus treatment enhances inhibitory immune checkpoint molecules' expression in monocyte-derived dendritic cells
Background Antigen-specific T-cell immunity is provided by dendritic cells (DCs), which are
specialized antigen-presenting cells. Furthermore, they establish a link between innate and …
specialized antigen-presenting cells. Furthermore, they establish a link between innate and …
RAD001-mediated mTOR targeting in human monocyte-derived dendritic cells shifts them toward an immunogenic phenotype
B Naseri, S Alipour, J Masoumi, A Hatami‐Sadr… - Immunologic …, 2025 - Springer
Dendritic cells (DCs) are essential for promoting T lymphocyte responses since they are
specialist antigen-presenting cells. In order to maintain tolerance or initiate immune …
specialist antigen-presenting cells. In order to maintain tolerance or initiate immune …
Exploring and exploiting the host cell autophagy during Mycobacterium tuberculosis infection
Tuberculosis, caused by Mycobacterium tuberculosis, is a fatal infectious disease that
prevails to be the second leading cause of death from a single infectious agent despite the …
prevails to be the second leading cause of death from a single infectious agent despite the …