Clusterin is a heterodimeric glycoprotein produced by a wide array of tissues and found in
most biologic fluids. A number of physiologic functions have been proposed for clusterin …

Complement regulatory proteins in glomerular diseases. Complement activation plays a
critical role in the pathogenesis of many forms of glomerulonephritis. Complement activation …

The human pathogen Streptococcus pyogenes possesses a chromosomal region, the mga
regulon, that contains co-regulated genes important to the virulence of these bacteria. A …

This study, designed and conducted as part of the International Life Sciences Institute
working group on the Application of Genomics and Proteomics, examined the changes in …

Clusterin/apoJ is an intriguing gene frequently isolated by differential screening in
laboratories from different areas of molecular biology, since it is overexpressed in numerous …

Apoliprotein J (apoJ)/clusterin has attracted considerable interest based on its inducibility in
multiple injury processes and accumulation at sites of remodeling, regression, and …

Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative
properties. Perturbations of cell interactions, an early event in acute renal injury, have …

Background Tubular biomarkers have been regarded as emerging and promising markers
for early diagnosis of diabetic kidney disease (DKD). The study was to determine the …

Renal repair begins soon after the kidney suffers ischemia-reperfusion injury (IRI); however,
its molecular pathways are not fully understood. Clusterin (Clu) is a chaperone protein with …

Chronic kidney disease (CKD) is a progressive pathological condition marked by
deteriorating renal function over time. Diagnostic of kidney disease depend on serum …