Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae

M Conrad, J Schothorst, HN Kankipati… - FEMS microbiology …, 2014 - academic.oup.com
The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies
on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been …

Coordination of microbial metabolism

V Chubukov, L Gerosa, K Kochanowski… - Nature Reviews …, 2014 - nature.com
Beyond fuelling cellular activities with building blocks and energy, metabolism also
integrates environmental conditions into intracellular signals. The underlying regulatory …

[HTML][HTML] Fructose-1, 6-bisphosphate couples glycolytic flux to activation of Ras

K Peeters, F Van Leemputte, B Fischer… - Nature …, 2017 - nature.com
Yeast and cancer cells share the unusual characteristic of favoring fermentation of sugar
over respiration. We now reveal an evolutionary conserved mechanism linking fermentation …

Flocculation, adhesion and biofilm formation in yeasts

KJ Verstrepen, FM Klis - Molecular microbiology, 2006 - Wiley Online Library
Yeast cells possess a remarkable capacity to adhere to abiotic surfaces, cells and tissues.
These adhesion properties are of medical and industrial relevance. Pathogenic yeasts such …

How Saccharomyces Responds to Nutrients

S Zaman, SI Lippman, X Zhao… - Annual review of …, 2008 - annualreviews.org
Yeast cells sense the amount and quality of external nutrients through multiple
interconnected signaling networks, which allow them to adjust their metabolism …

Glucose Signaling in Saccharomyces cerevisiae

GM Santangelo - Microbiology and Molecular Biology Reviews, 2006 - Am Soc Microbiol
Eukaryotic cells possess an exquisitely interwoven and fine-tuned series of signal
transduction mechanisms with which to sense and respond to the ubiquitous fermentable …

Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V‐ATPase

R Dechant, M Binda, SS Lee, S Pelet… - The EMBO …, 2010 - embopress.org
Glucose is the preferred carbon source for most cell types and a major determinant of cell
growth. In yeast and certain mammalian cells, glucose activates the cAMP‐dependent …

Confronting Maxwell's demon: biophysics of xylem embolism repair

MA Zwieniecki, NM Holbrook - Trends in plant science, 2009 - cell.com
Embolism results in a dramatic loss of xylem hydraulic transport capacity that can lead to
decreased plant productivity and even death. The ability to refill embolized conduits despite …

Intracellular pH is a tightly controlled signal in yeast

R Orij, S Brul, GJ Smits - Biochimica et Biophysica Acta (BBA)-General …, 2011 - Elsevier
BACKGROUND: Nearly all processes in living cells are pH dependent, which is why
intracellular pH (pHi) is a tightly regulated physiological parameter in all cellular systems …

Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

B Smets, R Ghillebert, P De Snijder, M Binda… - Current genetics, 2010 - Springer
Cells of all living organisms contain complex signal transduction networks to ensure that a
wide range of physiological properties are properly adapted to the environmental conditions …