Current trends in initial management of hypopharyngeal cancer: the declining use of open surgery

RP Takes, P Strojan, CE Silver, PJ Bradley… - Head & …, 2012 - Wiley Online Library
Squamous cell carcinoma of the hypopharynx represents a distinct clinical entity. Most
patients present with significant comorbidities and advanced‐stage disease. The overall …

Decision making in the management of recurrent head and neck cancer

AS Ho, DH Kraus, I Ganly, NY Lee, JP Shah… - Head & …, 2014 - Wiley Online Library
Despite substantial improvements in head and neck squamous cell carcinoma (HNSCC)
treatment, the major obstacle to long‐term survival remains disease recurrence. Salvage …

The current role of salvage surgery in recurrent head and neck squamous cell carcinoma

M Hamoir, S Schmitz, C Suarez, P Strojan… - Cancers, 2018 - mdpi.com
Chemoradiotherapy has emerged as a gold standard in advanced squamous cell carcinoma
of the head and neck (SCCHN). Because 50% of advanced stage patients relapse after …

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C18-ceramide in HNSCC …

S Karahatay, K Thomas, S Koybasi, CE Senkal… - Cancer letters, 2007 - Elsevier
It has been documented previously that defects in the generation of C18-ceramide, a
product of ceramide synthase 1 (CerS1), also known as longevity assurance gene 1 …

Salvage surgery in recurrent head and neck squamous cell carcinoma: oncologic outcome and predictors of disease free survival

M Hamoir, E Holvoet, J Ambroise, B Lengelé… - Oral oncology, 2017 - Elsevier
Objective Salvage surgery in recurrent SCCHN is associated with poor outcomes. This study
aimed to better identify suitable surgical candidates and those at high risk of new …

Salvage surgery in post-chemoradiation laryngeal and hypopharyngeal carcinoma: outcome and review

P VAN DER L, PA DOORNAERT… - Acta …, 2015 - pmc.ncbi.nlm.nih.gov
Our objective was to evaluate recurrence patterns of hypopharyngeal and laryngeal
carcinoma after chemoradiation and options for salvage surgery, with special emphasis on …

Salvage surgery for advanced stage head and neck squamous cell carcinoma following radiotherapy or chemoradiation

JBW Elbers, LI Veldhuis, PA Bhairosing… - European Archives of …, 2019 - Springer
Purpose Salvage surgery for recurrent advanced stage head and neck squamous cell
carcinoma (HNSCC) is known to result in poor prognosis. As there are only small and …

Survival and prognostic factors of different sites of head and neck cancer: an analysis from Thailand

K Pruegsanusak, S Peeravut, V Leelamanit… - Asian Pacific Journal …, 2012 - koreascience.kr
Background: Head and neck cancers are prevalent in Thailand, in particular in the southern
region of the country. However, survival with a large data set has not been reported. The …

Surgical salvage of recurrent cancer of the head and neck

M Zafereo - Current oncology reports, 2014 - Springer
The therapeutic options and prognosis for recurrent squamous cell carcinoma of the upper
aerodigestive tract vary greatly depending on site, extent of disease, and previous treatment …

Hypothyroidism and wound healing after salvage laryngectomy

AJ Rosko, AC Birkeland, E Bellile, KJ Kovatch… - Annals of surgical …, 2018 - Springer
Background Patients undergoing salvage laryngectomy are predisposed to radiation-
induced hypothyroidism and impaired wound healing secondary to the tissue effects of prior …