[HTML][HTML] Human neural stem/progenitor cells derived from embryonic stem cells and fetal nervous system present differences in immunogenicity and …

J Liu, C Götherström, M Forsberg, EB Samuelsson… - Stem cell …, 2013 - Elsevier
To develop cell therapies for damaged nervous tissue with human neural stem/progenitor
cells (hNPCs), the risk of an immune response and graft rejection must be considered. There …

[HTML][HTML] Loss of the protein cystathionine β-synthase during kidney injury promotes renal tubulointerstitial fibrosis

X Yuan, J Zhang, F Xie, W Tan, S Wang… - Kidney and Blood …, 2017 - karger.com
Background/Aims: Renal tubulointerstitial fibrosis (TIF) is the common pathway of
progressive chronic kidney disease. Inflammation has been widely accepted as the major …

Human parthenogenetic embryonic stem cell-derived neural stem cells express HLA-G and show unique resistance to NK cell-mediated killing

J Schmitt, S Eckardt, PG Schlegel, AL Sirén… - Molecular …, 2015 - Springer
Parent-of-origin imprints have been implicated in the regulation of neural differentiation and
brain development. Previously we have shown that, despite the lack of a paternal genome …

Calcineurin stimulates the expression of inflammatory factors in RAW 264.7 cells by interacting with proteasome subunit alpha type 6

W Zhang, Q Wei - Biochemical and biophysical research communications, 2011 - Elsevier
Calcineurin is the only Ca 2+-dependent serine/threonine-specific protein phosphatase and
is considered a potential regulator of many intracellular signaling events. In this study we …

Divergent effects of calcineurin Aβ on regulatory and conventional T-cell homeostasis

T Doetschman, A Sholl, H dau rw Chen, C Gard… - Clinical …, 2011 - Elsevier
Calcineurin (CN) is a phosphatase that activates nuclear factor of activated T cells (NFAT).
While the CN inhibitors cyclosporine A (CsA) and tacrolimus (FK506) can prevent graft …

The role of transforming growth factor beta signaling in inflammation-dependent colon cancer

C Ball - 2015 - search.proquest.com
Chronic inflammatory conditions such as Crohn's disease (CD) and Ulcerative colitis (UC)
are risk factors for colon cancer. TGFβ has been shown to be dysregulated in colon cancer …

[图书][B] Host responses to human neural cell therapy in spinal cord injury

J Liu - 2013 - search.proquest.com
Spinal cord injury (SCI) is a devastating condition without a cure. The SCI process
comprises an initially mechanical trauma and a secondary cascade of events including a …

[引用][C] DELINEATING THE ROLE OF CALCINEURIN A ALPHA IN THE MAST CELL FCϵRI-MEDIATED IMMUNE RESPONSE

E Leong - 2020