The blood-brain barrier: Physiology and strategies for drug delivery
The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper,
reflecting the unique requirements of the brain. In this review, following a brief historical …
reflecting the unique requirements of the brain. In this review, following a brief historical …
Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …
over conventional treatment methods. However, achieving high treatment efficacy and deep …
[HTML][HTML] Ultrasound neuromodulation: a review of results, mechanisms and safety
Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …
Ultrasound-mediated blood–brain barrier opening: An effective drug delivery system for theranostics of brain diseases
J Wang, Z Li, M Pan, M Fiaz, Y Hao, Y Yan… - Advanced Drug Delivery …, 2022 - Elsevier
Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …
Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
[HTML][HTML] Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer
At present, ultrasound radiation is broadly employed in medicine for both diagnostic and
therapeutic purposes at various frequencies and intensities. In this review article, we focus …
therapeutic purposes at various frequencies and intensities. In this review article, we focus …
Ultrasonic neuromodulation causes widespread cortical activation via an indirect auditory mechanism
T Sato, MG Shapiro, DY Tsao - Neuron, 2018 - cell.com
Ultrasound has received widespread attention as an emerging technology for targeted, non-
invasive neuromodulation based on its ability to evoke electrophysiological and motor …
invasive neuromodulation based on its ability to evoke electrophysiological and motor …
Modern methods for delivery of drugs across the blood–brain barrier
Y Chen, L Liu - Advanced drug delivery reviews, 2012 - Elsevier
The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
Evolving drug delivery strategies to overcome the blood brain barrier
DS Hersh, AS Wadajkar, NB Roberts… - Current …, 2016 - ingentaconnect.com
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
Engineering patient-specific cancer immunotherapies
Research into the immunological processes implicated in cancer has yielded a basis for the
range of immunotherapies that are now considered the fourth pillar of cancer treatment …
range of immunotherapies that are now considered the fourth pillar of cancer treatment …