Resting heart rate (RHR) is positively related with mortality. Regular exercise causes a
reduction in RHR. The aim of the systematic review was to assess whether regular exercise …

Current understanding on the mechanisms of brain injury and neurodegeneration highlights
an appreciation of multicellular interactions within the neurovascular unit (NVU), which …

Background Multimorbidity is an emerging public health priority. Physical activity (PA) is
recommended as one of the main lifestyle behaviours, yet the benefits of PA for people with …

En España, la declaración del estado de alarma por la pandemia Covid-19, supuso que
entre el 14 de marzo y el 2 de mayo de 2020, 47 millones de habitantes estuvieran …

The declaration of the COVID-19 pandemic has resulted in drastic changes to life worldwide.
In Spain, the state of alarm caused the confinement of 47 million inhabitants, affecting every …

The low rates of regular exercise and overall physical activity (PA) in the general population
represent a significant public health challenge. Previous research suggests that, for many …

Background It remains unclear what people are attempting to communicate, in terms of
objectively monitored behavior, when describing their physical activity and sedentary …

Mitochondria orchestrate the life and death of most eukaryotic cells by virtue of their ability to
supply adenosine triphosphate from aerobic respiration for growth, development, and …

Biological aging is associated with progressive damage accumulation, loss of organ
reserves, and systemic inflammation ('inflammaging'), which predispose for a wide spectrum …

The free radical theory of aging suggests that aging is caused by accumulation of damage
inflicted by reactive oxygen species (ROS). However, this concept has been very useful in …