Divalent Manganese Complexes as Potential Replacements for Gadolinium-Based Contrast Agents

P Caravan - Investigative Radiology, 2023 - journals.lww.com
Recent safety concerns surrounding the use of gadolinium-based contrast agents (GBCAs)
have spurred research into identifying alternatives to GBCAs for use with magnetic …

Circularly polarized activity from two photon excitable europium and samarium chiral bioprobes

S Mizzoni, S Ruggieri, A Sickinger, F Riobé… - Journal of Materials …, 2023 - pubs.rsc.org
In this contribution, two couples of cationic enantiomeric complexes [(R, R)-[LnL] Cl and (S,
S)-[LnL] Cl, with Ln= Sm and Eu and L= N, N′-bis (2-pyridylmethyl)-1, 2-(R, R or S, S) …

Thermodynamic stability of Mn (II) complexes with aminocarboxylate ligands analyzed using structural descriptors

R Uzal-Varela, F Pérez-Fernández, L Valencia… - Inorganic …, 2022 - ACS Publications
We present a quantitative analysis of the thermodynamic stabilities of Mn (II) complexes,
defined by the equilibrium constants (log K MnL values) and the values of pMn obtained as …

Donor radii in rare-earth complexes

C Harriswangler, JC Frías, MT Albelda… - Inorganic …, 2023 - ACS Publications
We present a set of donor radii for the rare-earth cations obtained from the analysis of
structural data available in the Cambridge Structural Database (CSD). Theoretical …

Synthesis and Photophysical Properties of Lanthanide Pyridinylphosphonic Tacn and Pyclen Derivatives: From Mononuclear Complexes to Supramolecular …

N Hamon, L Godec, E Jourdain… - Inorganic …, 2023 - ACS Publications
Synthetic methodologies were developed to achieve the preparation of ligands L1 and L2
consisting of tacn-and pyclen-based chelators decorated with pyridinylphosphonic pendant …

Rigid Fe (III) Chelate with Phosphonate Pendants: A Stable and Effective Extracellular MRI Contrast Agent

L He, H Wang, Z Zeng, L Zhong, Q Tang… - Journal of Medicinal …, 2024 - ACS Publications
A novel Fe (III) complex, Fe-t BPCDTA, was synthesized and explored as a potential contrast
agent for MRI. Compared to established agents like Fe-EDTA and Fe-t CDTA, Fe-t BPCDTA …

Physico-Chemical Characterization of a Highly Rigid Gd (III) Complex Formed with a Phenanthroline Derivative Ligand

B Váradi, N Lihi, S Bunda, A Nagy, G Simon… - Inorganic …, 2022 - ACS Publications
The discovery of the nephrogenic systemic fibrosis (NSF) and its link with the in vivo
dissociation of certain Gd (III)-based contrast agents (CAs) applied in the magnetic …

Chiral Pyclen-Based Heptadentate Chelates as Highly Stable MRI Contrast Agents

Y Jian, G Mo, W Xu, Y Liu, Z Zhang, Y Ding… - Inorganic …, 2024 - ACS Publications
In recent years, pyclen-based complexes have attracted a great deal of interest as magnetic
resonance imaging (MRI) contrast agents (CAs) and luminescent materials, as well as …

Structural Changes to the Gd‐DTPA Complex at Varying Ligand Protonation State

TJ Summers, RD O'Brien, JA Sobrinho… - European Journal of …, 2024 - Wiley Online Library
Diethylenetriaminepentaacetic acid (DTPA) is a chelating agent whose complex with the
Gd3+ ion is used in medical imaging. DTPA is also used in lanthanide‐actinide separation …

[HTML][HTML] Gadopiclenol: A q= 2 Gadolinium-Based MRI Contrast Agent Combining High Stability and Efficacy

I Maimouni, C Henoumont, MC De Goltstein… - Investigative …, 2023 - journals.lww.com
Objectives Gadopiclenol is aq= 2 pyclen gadolinium-based contrast agent (GBCA) recently
approved by the Food and Drug Administration, European Medicines Agency, and other …