For centuries, gold had been considered a precious, purely decorative inert metal. It was not
until 1986 that Ito and Hayashi described the first application of gold (I) in homogeneous …

This article outlines the benefits of using 'Design of Experiments'(DoE) optimisation during
the development of new synthetic methodology. A particularly important factor in the …

Nitrogen-containing heterocyclic compounds are worthy of attention for several reasons,
especially for their biological activities, which have led to the development of numerous …

Structurally, boronic acids are trivalent boron-containing organic compounds that possess
one alkyl substituent (ie, a C–B bond) and two hydroxyl groups to fill the remaining valences …

Benzoxaboraheterocycles (BOBs) are moieties of increasing interest in the pharmaceutical
industry; however, the synthesis of these compounds is often difficult or impractical due to …

Amide directed C–H borylation using≥ two equiv. of BBr3 forms borenium cations
containing a R2N (R′) CO→ B (Ar) Br unit which has significant Lewis acidity at the …

Substitutional doping of perylene with two boron atoms at the 6b/12b positions and two
oxygen or nitrogen atoms at the 1/7 positions has been achieved. The modular synthesis …

Simple borates serve as effective promoters for amide bond formation with a variety of
carboxylic acids and amines. With trimethyl or tris (2, 2, 2-trifluoroethyl) borate, amides are …

A cationic ruthenium (II) complex catalyzes double-bond transposition of 1, 1-di (boryl) alk-3-
enes to generate in situ 1, 1-di (boryl) alk-2-enes, which then undergo chiral phosphoric acid …

Treatment of benzofurans with bis (pinacolato) diboron and Cs2CO3 under nickel-NHC
catalysis resulted in the insertion of a boron atom into the C2–O bond of benzofurans to …