BACKGROUND Daratumumab (DARA), a promising novel therapy for multiple myeloma, is
an IgG1κ monoclonal antibody that recognizes CD38 on myeloma cells. During routine …

Autoimmune haemolytic anaemia (AIHA) is a rare autoimmune disease characterised by
haemolysis associated with the presence of immunoglobulins and/or components of the …

Cardiopulmonary bypass (CPB) during cardiac surgery can involve deliberate hypothermia
of the systemic (22-36° C) and coronary circulations (as low as 8-12° C). Adverse sequelae …

The Vel antigen is present on red blood cells (RBCs) from all humans except rare Vel-
negative individuals who can form antibodies to Vel in response to transfusion or pregnancy …

Objective We aimed to summarize the laboratory findings and clinical features of hemolytic
disease of the fetus and newborn (HDFN). Methods We retrospectively analyzed the data for …

The recommendations published in 20061 have been revised in the light of current scientific
evidence: the immunohaematological and instrumental investigations that should be …

Drug-induced immune hemolytic anemia is considered to be rare but is likely
underrecognized. The consulting pathologist plays a critical role in integrating serologic …

Ipilimumab, nivolumab, and pembrolizumab represent a new class of immunotherapeutic
drugs for treating patients with advanced cancer. Known as checkpoint inhibitors, these …

Background Administration of anti‐CD38 antibodies is a state‐of‐the‐art therapy for patients
diagnosed with multiple myeloma (MM). However, this treatment frequently leads to pan …

Abstract Background Scianna (Sc) antigens, seven high and two of low prevalence, are
expressed on erythrocyte membrane‐associated protein (ERMAP). We investigated SC …