Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate–protein interactions

Á Martínez, CO Mellet, JMG Fernández - Chemical Society Reviews, 2013 - pubs.rsc.org
Covalent attachment of biorecognizable sugar ligands in several copies at precise positions
of cyclomaltooligosaccharide (cyclodextrin, CD) macrocycles has proven to be an extremely …

Use of polyhedral oligomeric silsesquioxane (POSS) in drug delivery, photodynamic therapy and bioimaging

P Loman-Cortes, T Binte Huq, JL Vivero-Escoto - Molecules, 2021 - mdpi.com
Polyhedral oligomeric silsesquioxanes (POSS) have attracted considerable attention in the
design of novel organic-inorganic hybrid materials with high performance capabilities …

Polyhedral oligomeric silsesquioxane‐based nanoparticles for efficient chemotherapy of glioblastoma

X Zhong, G Wei, B Liu, C Wang, J Wang, Y Lu, W Cui… - Small, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most common lethal brain tumor with dismal treatment outcomes
and poor response to chemotherapy. As the regulatory center of cytogenetics and …

First-principles collision cross section measurements of large proteins and protein complexes

JW McCabe, CS Mallis, KI Kocurek… - Analytical …, 2020 - ACS Publications
Rotationally averaged collision cross section (CCS) values for a series of proteins and
protein complexes ranging in size from 8.6 to 810 kDa are reported. The CCSs were …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010

DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Chemically crosslinked amphiphilic degradable shape memory polymer nanocomposites with readily tuned physical, mechanical, and biological properties

X Xu, JD Skelly, J Song - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Facile surgical delivery and stable fixation of synthetic scaffolds play roles just as critically as
degradability and bioactivity in ensuring successful scaffold-guided tissue regeneration …

Fullerene‐sp2‐Iminosugar Balls as Multimodal Ligands for Lectins and Glycosidases: A Mechanistic Hypothesis for the Inhibitory Multivalent Effect

R Rísquez‐Cuadro… - … A European Journal, 2013 - Wiley Online Library
Concerted functioning of lectins and carbohydrate‐processing enzymes, mainly
glycosidases, is essential in maintaining life. It was commonly assumed that the …

A mannosylated pillar [5] arene derivative: chiral information transfer and antiadhesive properties against uropathogenic bacteria

I Nierengarten, K Buffet, M Holler, SP Vincent… - Tetrahedron …, 2013 - Elsevier
A pillar [5] arene derivative substituted with 10 peripheral acetylated mannosyl moieties has
been prepared by grafting an alkynylated mannose derivative onto the macrocyclic core …

Redefining protein interfaces within protein single crystals with DNA

BE Partridge, PH Winegar, Z Han… - Journal of the American …, 2021 - ACS Publications
Proteins are exquisite nanoscale building blocks: molecularly pure, chemically addressable,
and inherently selective for their evolved function. The organization of proteins into single …

The impact of heteromultivalency in lectin recognition and glycosidase inhibition: An integrated mechanistic study

MI García‐Moreno, F Ortega‐Caballero… - … A European Journal, 2017 - Wiley Online Library
The vision of multivalency as a strategy limited to achieve affinity enhancements between a
protein receptor and its putative sugar ligand (glycotope) has proven too simplistic. On the …