The role of imaging of flow patterns by 4D flow MRI in aortic stenosis

J Garcia, AJ Barker, M Markl - JACC: Cardiovascular Imaging, 2019 - jacc.org
Aortic valve stenosis (AS) is the most prevalent valvular heart disease in developed
countries and is associated with the development of severe secondary complications such …

Mechanisms of Aortic Dilation in Patients With Bicuspid Aortic Valve: JACC State-of-the-Art Review

JF Rodríguez-Palomares, L Dux-Santoy… - Journal of the American …, 2023 - jacc.org
Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

[HTML][HTML] Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve …

JΩF Rodríguez-Palomares, L Dux-Santoy… - Journal of …, 2018 - Elsevier
Background In patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be
caused by altered flow patterns and wall shear stress (WSS). These differences may explain …

Fully automated 3D aortic segmentation of 4D flow MRI for hemodynamic analysis using deep learning

H Berhane, M Scott, M Elbaz, K Jarvis… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To generate fully automated and fast 4D‐flow MRI‐based 3D segmentations of the
aorta using deep learning for reproducible quantification of aortic flow, peak velocity, and …

Aortic valve stenosis alters expression of regional aortic wall shear stress: New insights from a 4‐dimensional flow magnetic resonance imaging study of 571 subjects

P Van Ooij, M Markl, JD Collins, JC Carr… - Journal of the …, 2017 - Am Heart Assoc
Background Wall shear stress (WSS) is a stimulus for vessel wall remodeling. Differences in
ascending aorta (AA o) hemodynamics have been reported between bicuspid aortic valve …

Association of regional wall shear stress and progressive ascending aorta dilation in bicuspid aortic valve

G Soulat, MB Scott, BD Allen, R Avery, RO Bonow… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to evaluate the role of wall shear stress (WSS) as a
predictor of ascending aorta (AAo) growth at 5 years or greater follow-up. Background Aortic …

4D Flow with MRI

G Soulat, P McCarthy, M Markl - Annual review of biomedical …, 2020 - annualreviews.org
Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation
of patients with cardiac and vascular diseases. Since its introduction in the late 1980s …

4D flow MRI applications in congenital heart disease

J Rizk - European Radiology, 2021 - Springer
Advances in the diagnosis and management of congenital heart disease (CHD) have
resulted in a growing population of patients surviving well into adulthood and requiring …

Age‐related changes in aortic 3D blood flow velocities and wall shear stress: implications for the identification of altered hemodynamics in patients with aortic valve …

P Van Ooij, J Garcia, WV Potters… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To investigate age‐related changes in peak systolic aortic 3D velocity and wall
shear stress (WSS) in healthy controls and to investigate the importance of age‐matching for …

Normal patterns of thoracic aortic wall shear stress measured using four-dimensional flow MRI in a large population

FM Callaghan, SM Grieve - American Journal of Physiology …, 2018 - journals.physiology.org
Wall shear stress (WSS) plays a governing role in vascular remodeling and a pathogenic
role in vessel wall diseases. However, little is known of the normal WSS patterns in the aorta …