B cell generation of autoantibodies is a crucial step in the pathogenesis of systemic lupus
erythematosus (SLE). After their differentiation in the bone marrow, B cells populate the …

B cells have a pivotal function in the pathogenesis of autoimmune diseases, such as
rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus. In autoimmune …

The COVID-19 pandemic continues to cause severe global disruption, resulting in significant
excess mortality, overwhelming healthcare systems, and imposing substantial social and …

Autoimmune diseases strain healthcare systems worldwide as their incidence rises, and
current treatments put patients at risk for infections. An increased understanding of …

In response to inflammatory stimuli in conditions such as autoimmune disorders, infections
and cancers, immune cells organize in nonlymphoid tissues, which resemble secondary …

This study aimed at defining the role of the B cell adaptor protein BANK1 in the appearance
of age-associated B cells (ABCs) in 2 SLE mouse models (TLR7. tg6 and imiquimod …

Introduction MHC class II molecules are essential for appropriate immune responses against
pathogens but are also implicated in pathological responses in autoimmune diseases and …

In autoreactive germinal centers (GC) initiated by a single rogue B cell clone, wild-type B
cells expand and give rise to clones that target other autoantigens, known as epitope …

Altered composition of B‐cell compartments is a known feature in patients with systemic
lupus erythematosus (SLE). However, deep characterisation of B‐cell subsets and their …

In autoreactive germinal centers (GC) initiated by a single rogue B cell clone, wild-type B
cells expand and give rise to clones that target other autoantigens, known as epitope …