Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

This review covers reactions where iminium ions are likely to be active intermediates in the
catalytic cycle. The focus of the review is on synthetically useful protocols and smallmolecule …

We describe the preparation and characterization of photo-and mechanochromic 3D-printed
structures using a commercial fused filament fabrication printer. Three spiropyran-containing …

New molecular modeling approaches, driven by rapidly improving computational platforms,
have allowed many success stories for the use of computer-assisted drug design in the …

Hybrid molecules, furnished by combining two or more pharmacophores is an emerging
concept in the field of medicinal chemistry and drug discovery that has attracted substantial …

Thrombosis, which seriously endangers human health and life, is the leading cause of
morbidity and mortality globally. Antithrombotic drugs can interfere with the occurrence and …

A halogen bond catalyzed bromo‐carbocyclization of N‐cinnamyl sulfonamides and O‐
cinnamyl phenyl ethers has been developed. N‐methyl 4‐iodopyridinium triflate is used as …

Thrombosis is the leading cause of illness and mortality worldwide, posing a serious risk to
human health and life. Because antithrombotic drugs can prevent the beginning and …

Coagulation factor XII (FXII), a S1A serine protease, was discovered more than fifty years
ago. However, its in vivo functions and its three-dimensional structure started to be disclosed …

A large series of 3-carboxamido-7-substituted coumarins have been synthesized and tested
in vitro for their human monoamine oxidase A and B (hMAO-A and hMAO-B) inhibitory …