Antimicrobial peptides with anticancer activity: Today status, trends and their computational design
M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …
cancer cell lines. Various strategies for treating cancers with active peptides have been …
Unraveling the potential of M13 phages in biomedicine: Advancing drug nanodelivery and gene therapy
M13 phages possessing filamentous phage genomes offer the benefits of selective display
of molecular moieties and delivery of therapeutic agent payloads with a tolerable safety …
of molecular moieties and delivery of therapeutic agent payloads with a tolerable safety …
[HTML][HTML] Immunoinformatics-aided design of a peptide based multiepitope vaccine targeting glycoproteins and membrane proteins against monkeypox virus
Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …
An immunoinformatics study: designing multivalent T-cell epitope vaccine against canine circovirus
Background Canine circovirus is a deadly pathogen of dogs and causes vasculitis and
hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine …
hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine …
Design of a multi-epitope vaccine against the pathogenic fungi Candida tropicalis using an in silico approach
N Akhtar, A Singh, AK Upadhyay… - Journal of Genetic …, 2022 - Elsevier
Background Candida tropicalis causes tropical invasive fungal infections, with a high
mortality. This fungus has been found to be resistant to antifungal classes such as azoles …
mortality. This fungus has been found to be resistant to antifungal classes such as azoles …
[HTML][HTML] Designing of multi-epitope chimeric vaccine using immunoinformatic platform by targeting oncogenic strain HPV 16 and 18 against cervical cancer
Cervical cancer is the most common gynaecological cancer and reaches an alarming stage.
HPVs are considered the main causative agents for cervical cancer and other sexually …
HPVs are considered the main causative agents for cervical cancer and other sexually …
[HTML][HTML] Third-generation vaccines: features of nucleic acid vaccines and strategies to improve their efficiency
ARS Melo, LS de Macêdo, MCV Invenção, IA de Moura… - Genes, 2022 - mdpi.com
Gene immunization comprises mRNA and DNA vaccines, which stand out due to their
simple design, maintenance, and high efficacy. Several studies indicate promising results in …
simple design, maintenance, and high efficacy. Several studies indicate promising results in …
[HTML][HTML] A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice
P Zhou, Z Zhou, M Huayu, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Introduction The objective of this study is to construct a multi-epitope vaccine GILE
containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) …
containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) …
[HTML][HTML] In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant
Z Bahadori, M Shafaghi, H Madanchi… - Journal of translational …, 2022 - Springer
Background Streptococcus pneumoniae is the leading reason for invasive diseases
including pneumonia and meningitis, and also secondary infections following viral …
including pneumonia and meningitis, and also secondary infections following viral …
[HTML][HTML] Immunoinformatics-aided design of a new multi-epitope vaccine adjuvanted with domain 4 of pneumolysin against Streptococcus pneumoniae strains
M Shafaghi, Z Bahadori, H Madanchi, MM Ranjbar… - BMC …, 2023 - Springer
Abstract Background Streptococcus pneumoniae (Pneumococcus) has remained a leading
cause of fatal infections such as pneumonia, meningitis, and sepsis. Moreover, this …
cause of fatal infections such as pneumonia, meningitis, and sepsis. Moreover, this …