Antimicrobial peptides with anticancer activity: Today status, trends and their computational design

M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …

Unraveling the potential of M13 phages in biomedicine: Advancing drug nanodelivery and gene therapy

M Fadaie, H Dianat-Moghadam, E Ghafouri… - Environmental …, 2023 - Elsevier
M13 phages possessing filamentous phage genomes offer the benefits of selective display
of molecular moieties and delivery of therapeutic agent payloads with a tolerable safety …

[HTML][HTML] Immunoinformatics-aided design of a peptide based multiepitope vaccine targeting glycoproteins and membrane proteins against monkeypox virus

N Akhtar, V Kaushik, RK Grewal, AK Wani… - Viruses, 2022 - mdpi.com
Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …

An immunoinformatics study: designing multivalent T-cell epitope vaccine against canine circovirus

P Jain, A Joshi, N Akhtar, S Krishnan… - Journal of Genetic …, 2021 - Elsevier
Background Canine circovirus is a deadly pathogen of dogs and causes vasculitis and
hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine …

Design of a multi-epitope vaccine against the pathogenic fungi Candida tropicalis using an in silico approach

N Akhtar, A Singh, AK Upadhyay… - Journal of Genetic …, 2022 - Elsevier
Background Candida tropicalis causes tropical invasive fungal infections, with a high
mortality. This fungus has been found to be resistant to antifungal classes such as azoles …

[HTML][HTML] Designing of multi-epitope chimeric vaccine using immunoinformatic platform by targeting oncogenic strain HPV 16 and 18 against cervical cancer

A Kumar, U Sahu, P Kumari, A Dixit, P Khare - Scientific Reports, 2022 - nature.com
Cervical cancer is the most common gynaecological cancer and reaches an alarming stage.
HPVs are considered the main causative agents for cervical cancer and other sexually …

[HTML][HTML] Third-generation vaccines: features of nucleic acid vaccines and strategies to improve their efficiency

ARS Melo, LS de Macêdo, MCV Invenção, IA de Moura… - Genes, 2022 - mdpi.com
Gene immunization comprises mRNA and DNA vaccines, which stand out due to their
simple design, maintenance, and high efficacy. Several studies indicate promising results in …

[HTML][HTML] A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

P Zhou, Z Zhou, M Huayu, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Introduction The objective of this study is to construct a multi-epitope vaccine GILE
containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) …

[HTML][HTML] In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant

Z Bahadori, M Shafaghi, H Madanchi… - Journal of translational …, 2022 - Springer
Background Streptococcus pneumoniae is the leading reason for invasive diseases
including pneumonia and meningitis, and also secondary infections following viral …

[HTML][HTML] Immunoinformatics-aided design of a new multi-epitope vaccine adjuvanted with domain 4 of pneumolysin against Streptococcus pneumoniae strains

M Shafaghi, Z Bahadori, H Madanchi, MM Ranjbar… - BMC …, 2023 - Springer
Abstract Background Streptococcus pneumoniae (Pneumococcus) has remained a leading
cause of fatal infections such as pneumonia, meningitis, and sepsis. Moreover, this …