Estrogen governs the regulations of various pathological and physiological actions
throughout the body in both males and females. Generally, 17β-estradiol an endogenous …

Using cDNA cloning strategies commonly employed for G protein-coupled receptors
(GPCR), GPCR-30 (GPR30), was isolated from mammalian cells before knowledge of its …

Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …

A wide variety of environmental contaminants have been shown to exert estrogenic actions
in wildlife and laboratory animals through binding to nuclear estrogen receptors (ERs) and …

Background The incidence of obesity has risen dramatically over the last few decades. This
epidemic may be affected by exposure to xenobiotic chemicals. Bisphenol A (BPA), an …

It has become increasingly apparent that women suffer a disproportionate amount of pain
during their lifetime compared to men. Over the past 15 years, a growing number of studies …

Rationale: Although premenopausal females have a lower risk for cardiovascular disease,
the mechanism (s) are poorly understood. Objective: We tested the hypothesis that …

The effects of estrogen are widespread throughout the body. Although the classical nuclear
estrogen receptors have been known for many years to decades and their primary modes of …

Triple-negative breast cancer (TNBC) is a particularly aggressive and heterogeneous
disease with few effective targeted therapies and precision therapeutic options over a long …

G protein-coupled receptor 30 (GPR30), a seven-transmembrane receptor (7TMR), is
associated with rapid estrogen-dependent, G protein signaling and specific estrogen …