The population is aging at a rate never seen before in human history. As the number of
elderly adults grows, it is imperative we expand our understanding of the underpinnings of …

Merkel cell carcinoma (MCC) is a rare skin cancer characterized by neuroendocrine
differentiation. Its carcinogenesis is based either on the integration of the Merkel cell …

The number of older adults living with cancer is increasing. There is a clear lack of
representation of older adults in clinical trials, including cancer trials. Reasons for this are …

Older adults continue to be underrepresented in cancer clinical trials, despite most cancer
occurrence peaking in the later decades of life. Consequently, diagnostic and management …

Patients with urothelial carcinoma tend to be older and frailer with a large number of chronic
medical conditions. This is particularly pronounced in those with unresectable locally …

With the development of global social economy and the deepening of the aging population,
diseases related to aging have received increasing attention. The pathogenesis of many …

Objectives We aimed to determine the prognostic value of baseline Health-Related Quality
Of Life (HRQOL) and geriatric assessment (GA) to predict three-month mortality in older …

Elderly patients are the main users of drugs and they differ from younger patients. They are a
heterogeneous population that cannot be defined only by age but should rather be stratified …

Pancreatic cancer is one of the most lethal malignancies and is characterised by high-unmet
physical and psychological supportive care needs. Patient Reported Outcome Measures …

Background Co-existing frailty in older patients with hepatopancreaticobiliary (HPB)
malignancies is common. This study assessed the relationship between the Rockwood …