The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-
health problem of global dimensions. This type of antimicrobial resistance, especially when …

Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …

Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Treatment of infectious diseases becomes more challenging with each passing year. This is
especially true for infections caused by the opportunistic pathogen Pseudomonas …

Abstract Background Outer membrane vesicles (OMVs) are constitutively produced by Gram-
negative bacteria throughout growth and have proposed roles in virulence, inflammation …

The treatment of bacterial infections is increasingly complicated by the ability of bacteria to
develop resistance to antimicrobial agents. Antimicrobial agents are often categorized …