Organogenesis is a highly complex and precisely regulated process. Here we profiled the
chromatin accessibility in> 350,000 cells derived from 13 mouse embryos at four …

The Single-cell Assay for Transposase-Accessible Chromatin with high throughput
sequencing (scATAC-seq) has gained increasing popularity in recent years, allowing for …

Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Gonad development includes sex determination and divergent maturation of the testes and
ovaries. Recent advances in measuring gene expression in single cells are providing new …

Ploidy is relevant to numerous biological phenomena, including development, metabolism,
and tissue regeneration. Single-cell RNA-seq and other omics studies are revolutionizing …

The analysis of chromatin features in single cells centers around Tn5 transposase and
exploits its activity to simultaneously fragment target DNA and integrate adapter sequences …

Single-cell multi-omics sequencing has greatly accelerated reproductive research in recent
years, and the data are continually growing. However, utilizing these data resources is …

The biliary epithelial cells (cholangiocytes) in the liver originate from undifferentiated liver
parenchymal cells (hepatoblasts) that are located adjacent to the portal vein. This …

In mammals, early organogenesis begins soon after gastrulation, accompanied by
specification of various type of progenitor/precusor cells. In order to reveal dynamic …

Genomic sequencing data has revolutionized our understanding of the genetic basis of
biological processes. The cost of sequencing the first human genome was estimated to be …