Challenges in Acanthamoeba keratitis: a review

G Varacalli, A Di Zazzo, T Mori, TH Dohlman… - Journal of clinical …, 2021 - mdpi.com
To review challenges in the diagnosis and management of Acanthamoeba keratitis (AK),
along with prognostic factors, in order to help ophthalmologists avoid misdiagnosis …

Advances in the management of Acanthamoeba keratitis: a review of the literature and synthesized algorithmic approach

AR Kaufman, EY Tu - The Ocular Surface, 2022 - Elsevier
Acanthamoeba keratitis (AK) is a severe cause of infectious keratitis and represents a
significant clinical challenge. Recent literature regarding AK epidemiology, diagnosis …

Comparison of culture, confocal microscopy and PCR in routine hospital use for microbial keratitis diagnosis

JJ Hoffman, JKG Dart, SK De, N Carnt, G Cleary, S Hau - Eye, 2022 - nature.com
Aims To evaluate the sensitivity and specificity of polymerase chain reaction (PCR), in vivo
confocal microscopy (IVCM) and culture for microbial keratitis (MK) diagnosis. Methods …

Epidemiology of and Genetic Factors Associated with Acanthamoeba Keratitis

M Ilyas, F Stapleton, MDP Willcox, F Henriquez… - Pathogens, 2024 - mdpi.com
Acanthamoeba keratitis (AK) is a severe, rare protozoal infection of the cornea.
Acanthamoeba can survive in diverse habitats and at extreme temperatures. AK is mostly …

Understanding Acanthamoeba Keratitis: An in-depth review of a sight-threatening eye infection

F Petrillo, A Tortori, V Vallino, M Galdiero, AM Fea… - Microorganisms, 2024 - mdpi.com
Acanthamoeba keratitis (AK) is a rare but potentially sight-threatening corneal infection
caused by the Acanthamoeba parasite. This microorganism is found ubiquitously in the …

Utility of investigation for suspected microbial keratitis: a diagnostic accuracy study

S Tuft, C Bunce, S De, J Thomas - Eye, 2023 - nature.com
Purpose The true disease status of a population with suspected microbial keratitis (MK)
cannot be verified. There is not an accurate (gold) reference standard to confirm infection …

In vivo confocal microscopy of the inflamed anterior segment: A review of clinical and research applications

DV Patel, J Zhang, CNJ McGhee - Clinical & Experimental …, 2019 - Wiley Online Library
In vivo confocal microscopy (IVCM) allows non‐invasive imaging of the living human cornea,
specifically enabling the detection of immune cells in the healthy and diseased ocular …

AI-Based Decision-Support System for Diagnosing Acanthamoeba Keratitis Using In Vivo Confocal Microscopy Images

A Lincke, J Roth, AF Macedo… - … Vision Science & …, 2023 - tvst.arvojournals.org
Purpose: In vivo confocal microscopy (IVCM) of the cornea is a valuable tool for clinical
assessment of the cornea but does not provide stand-alone diagnostic support. The aim of …

Diagnosing and monitoring the characteristics of Acanthamoeba keratitis using slit scanning and laser scanning in vivo confocal microscopy

K Curro‐Tafili, FD Verbraak, R de Vries… - Ophthalmic and …, 2024 - Wiley Online Library
Introduction Acanthamoeba keratitis (AK) is a serious and potentially blinding ocular
infection caused by the free‐living amoeba, Acanthamoeba. In vivo confocal microscopy …

In vivo confocal microscopy morphologic features and cyst density in Acanthamoeba keratitis

R Chopra, PJ Mulholland, SC Hau - American Journal of Ophthalmology, 2020 - Elsevier
Purpose To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and
Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in …