Gastric cancer in Iran: epidemiology and risk factors

R Malekzadeh, MH Derakhshan, Z Malekzadeh - 2009 - sid.ir
Although the global incidence of GASTRIC CANCER has been decreased dramatically in
recent decades, it is the most common cancer in north and northwest IRAN. The wide …

Epidemiology of Helicobacter pylori infection

M Leja, A Axon, H Brenner - Helicobacter, 2016 - Wiley Online Library
This review of recent publications related to the epidemiology of Helicobacter pylori
highlights the origin of the infection, its changing prevalence, transmission, and outcome. A …

Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath …

A Idowu, A Mzukwa, U Harrison, P Palamides… - BMC …, 2019 - Springer
Background The global prevalence of H. pylori approaches 50%, with prevalence rates
between 20 and 40% in developed countries and up to 90% in Africa and other developing …

Clinical relevance of the cagA and vacA s1m1 status and antibiotic resistance in Helicobacter pylori: a systematic review and meta-analysis

M Karbalaei, A Talebi Bezmin Abadi, M Keikha - BMC Infectious Diseases, 2022 - Springer
Abstract Background The role of Helicobacter pylori (H. pylori) virulence factors of such as
vacA s1m1 and cagA in designating clinical outcomes and eradication rate has been deeply …

[HTML][HTML] Prevalence and factors associated with H. pylori infection in Saudi patients with dyspepsia

M Akeel, E Elmakki, A Shehata, A Elhafey… - Electronic …, 2018 - ncbi.nlm.nih.gov
Background Helicobacter pylori (H. pylori) is a major cause of peptic ulcer disease (PUD)
and chronic active gastritis that may progress to gastric cancer. Globally, it has been …

Association of Helicobacter pylori vacA genotypes and peptic ulcer in Iranian population: a systematic review and meta-analysis

M Keikha, M Ali-Hassanzadeh, M Karbalaei - BMC gastroenterology, 2020 - Springer
Background Helicobacter pylori is accounted as the most etiologic agent for digestive
disorders, in particular, the most important of them ie peptic ulcer and gastric cancer. In the …

Helicobacter pylori vacA, cagA and iceA genotypes in dyspeptic patients from southwestern region, Saudi Arabia: distribution and association with clinical outcomes …

M Akeel, A Shehata, A Elhafey, E Elmakki… - BMC …, 2019 - Springer
Background The aim of this study was to identify the common H. pylori virulence genes
among dyspeptic Southwestern Saudi patients and their association with clinical outcomes …

[HTML][HTML] Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?

DE Brennan, C Dowd, C O'Morain… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM To evaluate the association between virulence factor status and antibiotic resistance in
Helicobacter pylori (H. pylori)-infected patients in Ireland. METHODS DNA was extracted …

In silico study revealed the inhibitory activity of selected phytomolecules of C. rotundus against VacA implicated in gastric ulcer

H Atanda, TA Balogun, MM Alshehri… - Journal of …, 2023 - Taylor & Francis
Gastric ulcer is associated with weakening of the mucous coating of the stomach and
damages to the intestinal lining. It is caused by H. pylori assisted by enzymes including …

[HTML][HTML] Genetic analysis of cagA and vacA genes in Helicobacter pylori isolates and their relationship with gastroduodenal diseases in the west of Iran

N Souod, M Kargar, A Doosti, R Ranjbar… - Iranian Red Crescent …, 2013 - ncbi.nlm.nih.gov
Background Helicobacter pylori have different virulence factors which are associated with
several gastroduodenal diseases; however, this association is variable in different …