The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …

Significance: The imino acid proline is utilized by different organisms to offset cellular
imbalances caused by environmental stress. The wide use in nature of proline as a stress …

In recent years, vast amounts of data on the mechanisms of neural de-and regeneration
have accumulated. However, only in disproportionally few cases has this led to efficient …

Small organic molecules termed osmolytes are harnessed by a variety of cell types in a wide
range of organisms to counter unfavorable physiological conditions that challenge protein …

Significance: Proline metabolism has complex roles in a variety of biological processes,
including cell signaling, stress protection, and energy production. Proline also contributes to …

In adaptation biology the discovery of intracellular osmolyte molecules that in some cases
reach molar levels, raises questions of how they influence protein thermodynamics. We've …

This paper overviews solution additives that affect protein stability and aggregation during
refolding, heating, and freezing processes. Solution additives are mainly grouped into two …

The CRISPR-based nucleic acid detection systems have shown great potential for point-of-
care testing of viral pathogens, especially in the context of COVID-19 pandemic. Here we …

Molecular chaperone‐like activity for protein refolding was investigated using nanogels of
self‐assembly of cholesterol‐bearing pullulan. Nanogels effectively prevented protein …

Protein solubility and stability are issues of consideration in attempts to crystallize proteins.
These two properties of proteins are also at issue in the cells of organisms that have …