CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

C Li, E Brant, H Budak, B Zhang - Journal of Zhejiang University-SCIENCE …, 2021 - Springer
Since it was first recognized in bacteria and archaea as a mechanism for innate viral
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …

[HTML][HTML] CRISPR/Cas: A powerful tool for gene function study and crop improvement

D Zhang, Z Zhang, T Unver, B Zhang - Journal of Advanced Research, 2021 - Elsevier
Background It is a long-standing goal of scientists and breeders to precisely control a gene
for studying its function as well as improving crop yield, quality, and tolerance to various …

Application of CRISPR/Cas9 in crop quality improvement

Q Liu, F Yang, J Zhang, H Liu, S Rahman… - International Journal of …, 2021 - mdpi.com
The various crop species are major agricultural products and play an indispensable role in
sustaining human life. Over a long period, breeders strove to increase crop yield and …

Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus

S Tang, H Zhao, S Lu, L Yu, G Zhang, Y Zhang… - Molecular Plant, 2021 - cell.com
Seed oil content (SOC) is a highly important and complex trait in oil crops. Here, we
decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and …

Comparative genomic analyses reveal the genetic basis of the yellow-seed trait in Brassica napus

C Qu, M Zhu, R Hu, Y Niu, S Chen, H Zhao, C Li… - Nature …, 2023 - nature.com
Yellow-seed trait is a desirable breeding characteristic of rapeseed (Brassica napus) that
could greatly improve seed oil yield and quality. However, the underlying mechanisms …

CRISPR-based genome editing for nutrient enrichment in crops: a promising approach toward global food security

D Kumar, A Yadav, R Ahmad, UN Dwivedi… - Frontiers in …, 2022 - frontiersin.org
The global malnutrition burden imparts long-term developmental, economic, social, and
medical consequences to individuals, communities, and countries. The current …

Advances in crop breeding through precision genome editing

G Nerkar, S Devarumath, M Purankar, A Kumar… - Frontiers in …, 2022 - frontiersin.org
The global climate change and unfavourable abiotic and biotic factors are limiting
agricultural productivity and therefore intensifying the challenges for crop scientists to meet …

Anthocyanin biosynthesis genes as model genes for genome editing in plants

E Khusnutdinov, A Sukhareva, M Panfilova… - International journal of …, 2021 - mdpi.com
CRISPR/Cas, one of the most rapidly developing technologies in the world, has been
applied successfully in plant science. To test new nucleases, gRNA expression systems and …

The bibliometric landscape of gene editing innovation and regulation in the worldwide

X Wei, A Pu, Q Liu, Q Hou, Y Zhang, X An, Y Long… - Cells, 2022 - mdpi.com
Gene editing (GE) has become one of the mainstream bioengineering technologies over the
past two decades, mainly fueled by the rapid development of the CRISPR/Cas system since …

Base editing with high efficiency in allotetraploid oilseed rape by A3A‐PBE system

H Cheng, M Hao, B Ding, D Mei… - Plant biotechnology …, 2021 - Wiley Online Library
CRISPR/Cas‐base editing is an emerging technology that could convert a nucleotide to
another type at the target site. In this study, A3A‐PBE system consisting of human A3A …