Pulmonary invasive mucinous adenocarcinoma

WC Chang, YZ Zhang, AG Nicholson - Histopathology, 2024 - Wiley Online Library
Invasive mucinous adenocarcinoma (IMA) is a relatively rare subtype of lung
adenocarcinoma, composed of goblet and/or columnar tumour cells containing abundant …

Multiple primary lung cancers: a new challenge in the era of precision medicine

L Zhao, C Liu, G Xie, F Wu, C Hu - Cancer Management and …, 2020 - Taylor & Francis
With the widespread implementation of lung cancer screening, more and more patients are
being diagnosed with multiple primary lung cancers (MPLCs). In the era of precision …

[HTML][HTML] Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers

C Hu, L Zhao, W Liu, S Fan, J Liu, Y Liu… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Diagnosing and treating patients with multiple primary lung cancers (MPLCs)
bring challenges to the clinic, and the preliminary evidence has revealed unsatisfying …

Comprehensive next-generation sequencing unambiguously distinguishes separate primary lung carcinomas from intrapulmonary metastases: comparison with …

JC Chang, D Alex, M Bott, KS Tan, V Seshan… - Clinical Cancer …, 2019 - AACR
Purpose: In patients with> 1 non–small cell lung carcinoma (NSCLC), the distinction
between separate primary lung carcinomas (SPLCs) and intrapulmonary metastases (IPMs) …

Invasive mucinous adenocarcinomas with spatially separate lung lesions: analysis of clonal relationship by comparative molecular profiling

SR Yang, JC Chang, C Leduc, KS Tan, S Dogan… - Journal of Thoracic …, 2021 - Elsevier
Introduction Pulmonary invasive mucinous adenocarcinomas (IMAs) often present with
spatially separate lung lesions. Clonal relationship between such lesions, particularly those …

Genomic staging of multifocal lung squamous cell carcinomas is independent of the comprehensive morphologic assessment

S Dacic, X Cao, N Bota-Rabassedas… - Journal of Thoracic …, 2024 - Elsevier
Introduction Morphologic and molecular data for staging of multifocal lung squamous cell
carcinomas (LSCCs) are limited. In this study, whole exome sequencing (WES) was used as …

Surgical prognosis of synchronous multiple primary lung cancer: Systematic review and meta-analysis

Y Nie, X Wang, F Yang, Z Zhou, J Wang, K Chen - Clinical lung cancer, 2021 - Elsevier
Background We evaluated the long-term prognosis of synchronous multiple primary lung
cancer (SMPLC) patients after surgical treatment and explored prognostic factors for overall …

[HTML][HTML] Genomic profiling with large-scale next-generation sequencing panels distinguishes separate primary lung adenocarcinomas from intrapulmonary …

CY Yang, YC Yeh, LC Wang, YY Lin, SY Lin, SY Wang… - Modern Pathology, 2023 - Elsevier
The distinction between different separate primary lung cancers (SPLCs) and
intrapulmonary metastases (IPMs) is a challenging but clinically significant issue …

Lineage tracing for multiple lung cancer by spatiotemporal heterogeneity using a multi-omics analysis method integrating genomic, transcriptomic, and immune …

Y Song, J Zhou, X Zhao, Y Zhang, X Xu… - Frontiers in …, 2023 - frontiersin.org
Introduction The distinction between multiple primary lung cancer (MPLC) and
intrapulmonary metastasis (IPM) holds clinical significance in staging, therapeutic …

Molecular identification and genetic characterization of early-stage multiple primary lung cancer by large-panel next-generation sequencing analysis

G Pei, M Li, X Min, Q Liu, D Li, Y Yang, S Wang… - Frontiers in …, 2021 - frontiersin.org
Objective The incidence of early stage multiple primary lung cancer (MPLC) has been
increasing in recent years, while the ideal strategy for its diagnosis and treatment remains …