[HTML][HTML] Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort

EC Goligher, AH Jonkman, J Dianti, K Vaporidi… - Intensive care …, 2020 - Springer
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Mechanical ventilation: state of the art

T Pham, LJ Brochard, AS Slutsky - Mayo Clinic Proceedings, 2017 - Elsevier
Mechanical ventilation is the most used short-term life support technique worldwide and is
applied daily for a diverse spectrum of indications, from scheduled surgical procedures to …

Myocardial infarction, stroke, and pulmonary embolism after BNT162b2 mRNA COVID-19 vaccine in people aged 75 years or older

MJ Jabagi, J Botton, M Bertrand, A Weill, P Farrington… - Jama, 2022 - jamanetwork.com
Methods| This population-based study used the French National Health Data System linked
to the national COVID-19 vaccination database. Eligible participants were all persons …

Lung-and diaphragm-protective ventilation

EC Goligher, M Dres, BK Patel, SK Sahetya… - American journal of …, 2020 - atsjournals.org
Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is associated
with poor clinical outcomes. Although the importance and impact of lung-protective …

Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs low PEEP on mortality in patients with acute respiratory distress syndrome: a …

AB Cavalcanti, ÉA Suzumura, LN Laranjeira… - Jama, 2017 - jamanetwork.com
Importance The effects of recruitment maneuvers and positive end-expiratory pressure
(PEEP) titration on clinical outcomes in patients with acute respiratory distress syndrome …

Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Patient-self inflicted lung injury: a practical review

G Carteaux, M Parfait, M Combet… - Journal of clinical …, 2021 - mdpi.com
Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

The future of mechanical ventilation: lessons from the present and the past

L Gattinoni, JJ Marini, F Collino, G Maiolo, F Rapetti… - Critical Care, 2017 - Springer
The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …

Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome

Y Zhou, X Jin, Y Lv, P Wang, Y Yang, G Liang… - Intensive care …, 2017 - Springer
Purpose Experimental animal models of acute respiratory distress syndrome (ARDS) have
shown that the updated airway pressure release ventilation (APRV) methodologies may …

Airway occlusion pressure as an estimate of respiratory drive and inspiratory effort during assisted ventilation

I Telias, D Junhasavasdikul, N Rittayamai… - American journal of …, 2020 - atsjournals.org
Rationale: Monitoring and controlling respiratory drive and effort may help to minimize lung
and diaphragm injury. Airway occlusion pressure (P0. 1) is a noninvasive measure of …