The molecular diversity of glycosaminoglycans shapes animal development

HE Bülow, O Hobert - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
Proteoglycans (PGs), molecules in which glycosaminoglycans (GAGs) are covalently linked
to a protein core, are components of the extracellular matrix of all multicellular organisms …

From nose to brain: development of gonadotrophin‐releasing hormone‐1 neurones

S Wray - Journal of neuroendocrinology, 2010 - Wiley Online Library
Gonadotrophin‐releasing hormone‐1 (GnRH‐1) is essential for mammalian reproduction,
controlling release of gonadotrophins from the anterior pituitary. GnRH‐1 neurones migrate …

Differential sulfations and epimerization define heparan sulfate specificity in nervous system development

HE Bülow, O Hobert - Neuron, 2004 - cell.com
Heparan sulfate proteoglycans (HSPG) are components of the extracellular matrix through
which axons navigate to reach their targets. The heparan sulfate (HS) side chains of HSPGs …

Gonadotropin-releasing hormone (GnRH) neuron migration: initiation, maintenance and cessation as critical steps to ensure normal reproductive function

ME Wierman, K Kiseljak-Vassiliades, S Tobet - Frontiers in …, 2011 - Elsevier
GnRH neurons follow a carefully orchestrated journey from their birth in the olfactory
placode area. Initially, they migrate along with the vomeronasal nerve into the brain at the …

[HTML][HTML] Epidermal morphogenesis

AD Chisholm, J Hardin - WormBook: The Online Review of C …, 2005 - ncbi.nlm.nih.gov
The morphogenesis of the C. elegans embryo is largely controlled by the development of the
epidermis, also known as the hypodermis, a single epithelial layer that surrounds the …

Evolving concepts in human renal dysplasia

AS Woolf, KL Price, PJ Scambler… - Journal of the American …, 2004 - journals.lww.com
Human renal dysplasia is a collection of disorders in which kidneys begin to form but then
fail to differentiate into normal nephrons and collecting ducts. Dysplasia is the principal …

Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1

HE Bülow, KL Berry, LH Topper… - Proceedings of the …, 2002 - National Acad Sciences
Kallmann syndrome is a neurological disorder characterized by various behavioral and
neuroanatomical defects. The X-linked form of this disease is caused by mutations in the …

The Caenorhabditis elegans epidermis as a model skin. I: development, patterning, and growth

AD Chisholm, TI Hsiao - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
The skin of the nematode Caenorhabditis elegans is composed of a simple epidermal
epithelium and overlying cuticle. The skin encloses the animal and plays central roles in …

A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3

W Yuan, Y Rao, RP Babiuk, J Greer… - Proceedings of the …, 2003 - National Acad Sciences
Congenital diaphragmatic hernia (CDH) is a significant cause of pediatric mortality in
humans with a heterogeneous and poorly understood etiology. Here we show that mice …

Novel innate immune functions of the whey acidic protein family

CD Bingle, A Vyakarnam - Trends in immunology, 2008 - cell.com
Studies on the interaction of HIV with host factors have recently highlighted a potential role
in the pathogenesis of AIDS for three distinct members of the whey acidic protein (WAP) …