IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international
collaborative efforts have led to important discoveries that have improved our understanding …

IgA nephropathy (IgAN) is the most common type of glomerulonephritis in Asia and the
Western world. In most patients, it follows an asymptomatic to oligosymptomatic course and …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Importance Guidelines recommend corticosteroids in patients with IgA nephropathy and
persistent proteinuria, but the effects remain uncertain. Objective To evaluate the efficacy …

Background IgA nephropathy is thought to be associated with mucosal immune system
dysfunction, which manifests as renal IgA deposition that leads to impairment and end-stage …

Background The outcomes of immunosuppressive therapy, when added to supportive care,
in patients with IgA nephropathy are uncertain. Methods We conducted a multicenter, open …

IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved
therapies. A challenge for evaluating treatments for IgAN is the usual long time course for …

Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

IgA nephropathy frequently leads to progressive CKD. Although interest surrounds use of
immunosuppressive agents added to standard therapy, several recent studies have …

The randomized, controlled STOP-IgAN trial in patients with IgA nephropathy (IgAN) and
substantial proteinuria showed no benefit of immunosuppression added on top of supportive …