Inhalation drug delivery in combating pulmonary infections: Advances and challenges
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …
world. The clinical applications of a variety of therapeutics approved for PIs have been …
Dissecting the in vitro fate of plant-derived bioactive encapsulated nanoparticles in lung diseases
Lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung
cancer are prevalent worldwide, with high mortality rates. There are many pathways …
cancer are prevalent worldwide, with high mortality rates. There are many pathways …
Polysaccharide, fecal microbiota, and curcumin-based novel oral colon-targeted solid self-nanoemulsifying delivery system: Formulation, characterization, and in-vitro …
The use of polysaccharides in preparation of microbially triggered colon-targeted delivery
system has been explored extensively to deliver drugs at the colonic site. This type of …
system has been explored extensively to deliver drugs at the colonic site. This type of …
18-β-Glycyrrhetinic acid encapsulated PLGA nanoparticles attenuate lung cancer proliferation and migration
KR Paudel, MSB Mohamad, G De Rubis… - Journal of Drug Delivery …, 2024 - Elsevier
Conventional treatment methods to treat lung cancer include radiation therapy,
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …
Carrier Systems for Advanced Drug Delivery: Improving Drug Solubility/Bioavailability and Administration Routes
S Losada-Barreiro, S Celik, Z Sezgin-Bayindir… - Pharmaceutics, 2024 - mdpi.com
The disadvantages of some conventional drugs, including their low bioavailability, poor
targeting efficiency, and important side effects, have led to the rational design of drug …
targeting efficiency, and important side effects, have led to the rational design of drug …
Application of quality by design in optimization of nanoformulations: Principle, perspectives and practices
D Birla, N Khandale, B Bashir, M ShahbazAlam… - Drug Delivery and …, 2024 - Springer
Nanoparticulate drug delivery systems (NDDS) based nanoformulations have emerged as
promising drug delivery systems. Various NDDS-based formulations have been reported …
promising drug delivery systems. Various NDDS-based formulations have been reported …
Polymeric Micelles Loaded In Situ Gel with Prednisolone Acetate for Ocular Inflammation: Development and Evaluation
Aim: Our study developed a prednisolone acetate polymeric micelles (PM) system for ocular
inflammation related to allergic uveitis. Methods: For PM development, a thin-film hydration …
inflammation related to allergic uveitis. Methods: For PM development, a thin-film hydration …
Polysaccharide-fecal microbiota-based colon-targeted self-nanoemulsifying drug delivery system of curcumin for treating polycystic ovarian syndrome
The gut microbiome is involved in the pathogenesis of many diseases including polycystic
ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and …
ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and …
Response surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity …
Vanillic acid (VA) is a phenolic compound with potential antioxidant activity, which improves
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …
Polymeric micelles as potent islet amyloid inhibitors: current advances and future perspectives
Highlights•Clinical studies claimed islet amyloidosis as a histopathological feature of
diabetes.•Existing treatment strategies are restricted to blood glucose control only.•Micelles …
diabetes.•Existing treatment strategies are restricted to blood glucose control only.•Micelles …