Inhalation drug delivery in combating pulmonary infections: Advances and challenges

P Kumbhar, J Kaur, G De Rubis, KR Paudel… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …

Dissecting the in vitro fate of plant-derived bioactive encapsulated nanoparticles in lung diseases

AB Saeid, VK Patel, S Mehndiratta, R Rajput… - Food Bioscience, 2023 - Elsevier
Lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung
cancer are prevalent worldwide, with high mortality rates. There are many pathways …

Polysaccharide, fecal microbiota, and curcumin-based novel oral colon-targeted solid self-nanoemulsifying delivery system: Formulation, characterization, and in-vitro …

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Materials Today …, 2022 - Elsevier
The use of polysaccharides in preparation of microbially triggered colon-targeted delivery
system has been explored extensively to deliver drugs at the colonic site. This type of …

18-β-Glycyrrhetinic acid encapsulated PLGA nanoparticles attenuate lung cancer proliferation and migration

KR Paudel, MSB Mohamad, G De Rubis… - Journal of Drug Delivery …, 2024 - Elsevier
Conventional treatment methods to treat lung cancer include radiation therapy,
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …

Carrier Systems for Advanced Drug Delivery: Improving Drug Solubility/Bioavailability and Administration Routes

S Losada-Barreiro, S Celik, Z Sezgin-Bayindir… - Pharmaceutics, 2024 - mdpi.com
The disadvantages of some conventional drugs, including their low bioavailability, poor
targeting efficiency, and important side effects, have led to the rational design of drug …

Application of quality by design in optimization of nanoformulations: Principle, perspectives and practices

D Birla, N Khandale, B Bashir, M ShahbazAlam… - Drug Delivery and …, 2024 - Springer
Nanoparticulate drug delivery systems (NDDS) based nanoformulations have emerged as
promising drug delivery systems. Various NDDS-based formulations have been reported …

Polymeric Micelles Loaded In Situ Gel with Prednisolone Acetate for Ocular Inflammation: Development and Evaluation

N Kaushal, M Kumar, A Tiwari, V Tiwari, K Sharma… - …, 2023 - Taylor & Francis
Aim: Our study developed a prednisolone acetate polymeric micelles (PM) system for ocular
inflammation related to allergic uveitis. Methods: For PM development, a thin-film hydration …

Polysaccharide-fecal microbiota-based colon-targeted self-nanoemulsifying drug delivery system of curcumin for treating polycystic ovarian syndrome

L Corrie, H Singh, M Gulati, S Vishwas… - Naunyn-Schmiedeberg's …, 2024 - Springer
The gut microbiome is involved in the pathogenesis of many diseases including polycystic
ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and …

Response surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity …

MHS Dawoud, MA Zaafan, SS Saleh… - Drug delivery and …, 2023 - Springer
Vanillic acid (VA) is a phenolic compound with potential antioxidant activity, which improves
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …

Polymeric micelles as potent islet amyloid inhibitors: current advances and future perspectives

J Kaur, M Gulati, IP Kaur, V Patravale, K Dua… - Drug Discovery …, 2023 - Elsevier
Highlights•Clinical studies claimed islet amyloidosis as a histopathological feature of
diabetes.•Existing treatment strategies are restricted to blood glucose control only.•Micelles …