DNA has played an early and powerful role in the development of bottom-up
nanotechnologies, not least because of DNA's precise, predictable, and controllable …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

The intriguing structural diversity in folded topologies available to guanine-rich nucleic acid
repeat sequences have made four-stranded G-quadruplex structures the focus of both basic …

Approximately 13% of the human genome can fold into non-canonical (non-B) DNA
structures (eg G-quadruplexes, Z-DNA, etc.), which have been implicated in vital cellular …

Guanine-rich DNA sequences can form G-quadruplexes stabilized by stacked G–G–G–G
tetrads in monovalent cation-containing solution. The length and number of individual G …

G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …

Mounting evidence supports the presence of biologically relevant G‐quadruplexes in single‐
cell organisms, but the existence of endogenous G‐quadruplex structures in mammalian …

The excessive production of reactive oxygen species (ROS) can lead to single nucleic acid
base damage, DNA strand breakage, inter-and intra-strand cross-linking of nucleic acids …

G-quadruplexes are guanine-rich nucleic acids that fold by forming successive quartets of
guanines (the G-tetrads), stabilized by intra-quartet hydrogen bonds, inter-quartet stacking …

Four‐stranded G‐rich DNA structures called G‐quadruplexes have been the subject of
increasing interest recently. Experimental and computational techniques have been used to …