Oxidative stress and neural dysfunction in gastrointestinal diseases: can stem cells offer a solution?
Oxidative stress is involved in many gastrointestinal (GI) disorders as either the primary
pathogenesis (radiation, chemotherapy, toxicity, ischemia-reperfusion) or a secondary …
pathogenesis (radiation, chemotherapy, toxicity, ischemia-reperfusion) or a secondary …
Therapeutic potential of Nrf-2 pathway in the treatment of diabetic neuropathy and nephropathy
Abstract Type 2 diabetes (T2D) is one of the most widely spread metabolic disordersand is
also referred as a 'lifestyle'disorder. According toa study conducted by IDB, the number of …
also referred as a 'lifestyle'disorder. According toa study conducted by IDB, the number of …
Intrathecal umbilical cord mesenchymal stem cells injection alleviates neuroinflammation and oxidative stress in the cyclophosphamide-induced interstitial cystitis rats …
Q Gao, Y Zhao, R Luo, M Su, C Zhang, C Li, B Liu… - Life Sciences, 2023 - Elsevier
Aims Neuroinflammation in the spinal dorsal horn (SDH) region plays an important role in
the pathogenesis of interstitial cystitis (IC)/bladder pain syndrome (BPS). Oxidative stress is …
the pathogenesis of interstitial cystitis (IC)/bladder pain syndrome (BPS). Oxidative stress is …
Characterization of β-cyclodextrin Hybridized Diatomite as Potential Delivery Systems of Oxaliplatin and 5-Fluorouracil Drugs; Equilibrium Modeling of Loading and …
HE Alfassam, SI Al Othman, MA Al-Waili… - … Science, Part B, 2023 - Taylor & Francis
The present study involved the functionalization of diatomite's bio-siliceous frustules with
polymeric chains of β-cyclodextrin (β-CD/Di) to serve as advanced delivery structures for the …
polymeric chains of β-cyclodextrin (β-CD/Di) to serve as advanced delivery structures for the …
Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in …
ALL Oliveira, GGL Santos… - Stem cells …, 2021 - Wiley Online Library
Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum‐derivative
chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors …
chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors …
Platinum-induced peripheral neuropathy (PIPN): ROS-related mechanism, therapeutic agents, and nanosystems
X Hu, Z Jiang, L Teng, H Yang, D Hong… - Frontiers in Molecular …, 2021 - frontiersin.org
Platinum (Pt) drugs (eg, oxaliplatin, cisplatin) are applied in the clinic worldwide for the
treatment of various cancers. However, platinum-induced peripheral neuropathy (PIPN) …
treatment of various cancers. However, platinum-induced peripheral neuropathy (PIPN) …
Bone marrow‐derived mesenchymal stem cells attenuate complete Freund's a djuvant‐induced inflammatory pain by inhibiting the expression of P2X3
Y Deng, D Yuan, Z Deng, J Liang, Z Zhang… - Cell …, 2023 - Wiley Online Library
Bone marrow‐derived mesenchymal stem cells (BMSCs) show a good property for pain
treatment by modulating inflammatory response. However, the underlying therapeutic effect …
treatment by modulating inflammatory response. However, the underlying therapeutic effect …
Exploring the Role of Mesenchymal Stem Cell–Derived Exosomes in Diabetic and Chemotherapy-Induced Peripheral Neuropathy
LA Ahmed, KF Al-Massri - Molecular Neurobiology, 2024 - Springer
Diabetic and chemotherapy-induced peripheral neuropathies are known for long-term
complications that are associated with uncontrolled hyperglycemia and cancer treatment …
complications that are associated with uncontrolled hyperglycemia and cancer treatment …
Characterization of Chitosan-Hybridized Diatomite as Potential Delivery Systems of Oxaliplatin and 5-Fluorouracil Drugs: Equilibrium and Release Kinetics
The current work involves the modification of diatomite's biosiliceous frustules employing
chitosan polymer chains (CS/Di) to serve as low-cost, biocompatible, multifunctional, and …
chitosan polymer chains (CS/Di) to serve as low-cost, biocompatible, multifunctional, and …
[HTML][HTML] The effects of mesenchymal stem cells on the chemotherapy of colorectal cancer
M Wang, J Li, D Wang, Y Xin, Z Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Colorectal cancer (CRC) has been the third commonest cancer in the world. The prognosis
of patients with CRC is related to the molecular subtypes and gene mutations, which is …
of patients with CRC is related to the molecular subtypes and gene mutations, which is …