Challenges in exploring and manipulating the human skin microbiome

M Boxberger, V Cenizo, N Cassir, B La Scola - Microbiome, 2021 - Springer
The skin is the exterior interface of the human body with the environment. Despite its harsh
physical landscape, the skin is colonized by diverse commensal microbes. In this review, we …

Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

[PDF][PDF] Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor

A Uberoi, C Bartow-McKenney, Q Zheng, L Flowers… - Cell host & …, 2021 - cell.com
The epidermis forms a barrier that defends the body from desiccation and entry of harmful
substances, while also sensing and integrating environmental signals. The tightly …

Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics

JH Jo, CP Harkins, NH Schwardt, JA Portillo… - Science translational …, 2021 - science.org
Although systemic antibiotics are critical in controlling infections and reducing morbidity and
mortality, overuse of antibiotics is presumed to contribute to negative repercussions such as …

[PDF][PDF] Bacteria induce skin regeneration via IL-1β signaling

G Wang, E Sweren, H Liu, E Wier, MP Alphonse… - Cell host & …, 2021 - cell.com
Environmental factors that enhance regeneration are largely unknown. The immune system
and microbiome are attributed roles in repairing and regenerating structure but their precise …

The skin and intestinal microbiota and their specific innate immune systems

M Coates, MJ Lee, D Norton, AS MacLeod - Frontiers in immunology, 2019 - frontiersin.org
The skin and intestine are active organs of the immune system that are constantly exposed
to the outside environment. They support diverse microbiota, both commensal and …

In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

MAT Blaskovich, AG Elliott, AM Kavanagh, S Ramu… - Scientific reports, 2019 - nature.com
Acne is a common skin affliction that involves excess sebum production and modified lipid
composition, duct blockage, colonization by bacteria, and inflammation. Acne drugs target …

Role of wound microbiome, strategies of microbiota delivery system and clinical management

Q Tang, N Xue, X Ding, KHY Tsai, JJ Hew… - Advanced Drug Delivery …, 2023 - Elsevier
Delayed wound healing is one of the most global public health threats affecting nearly 100
million people each year, particularly the chronic wounds. Many confounding factors such as …

[HTML][HTML] Human microbiome: composition and role in inflammatory skin diseases

A Balato, S Cacciapuoti, R Di Caprio… - Archivum immunologiae …, 2019 - Springer
This review focuses on recent evidences about human microbiome composition and
functions, exploring the potential implication of its impairment in some diffuse and …

Smarter cures to combat COVID-19 and future pathogens: a review

H Dai, J Han, E Lichtfouse - Environmental Chemistry Letters, 2021 - Springer
Prevention is better than cure. A milestone of the anthropocene is the emergence of a series
of epidemics and pandemics often characterized by the transmission of a pathogen from …