A review of chemical constituents and health-promoting effects of citrus peels

N Liu, X Li, P Zhao, X Zhang, O Qiao, L Huang, L Guo… - Food chemistry, 2021 - Elsevier
Citrus is one of the main fruits processed worldwide, producing a lot of industrial by-
products. As the main part of citrus “residue”, citrus peels have a wide application prospect …

Phytochemistry and biological activities of Citrus sinensis and Citrus limon: An update

S Zahr, R Zahr, R El Hajj, M Khalil - Journal of Herbal Medicine, 2023 - Elsevier
Introduction Citrus is among the main tree crops cultivated worldwide, with orange and
lemon being well-known species. In this review, a thorough investigation of literature was …

Novel active edible food packaging films based entirely on citrus peel wastes

RKS Khalil, MR Sharaby, DS Abdelrahim - Food Hydrocolloids, 2023 - Elsevier
This is the first report on mobilizing three value-added compounds from citrus peel wastes to
fabricate novel/cost-effective active edible films with multiple functionalities. Pectin extracted …

Polyphenol mechanisms against gastric cancer and their interactions with gut microbiota: a review

M Li, Y Zheng, J Zhao, M Liu, X Shu, Q Li, Y Wang… - Current …, 2022 - mdpi.com
The lack of new drugs and resistance to existing drugs are serious problems in gastric
cancer (GC) treatment. The research found polyphenols possess anti-Helicobacter pylori …

Inhibition of Enzymes Involved in Neurodegenerative Disorders and Aβ1–40 Aggregation by Citrus limon Peel Polyphenol Extract

R Arcone, A D'Errico, R Nasso, R Rullo, A Poli… - Molecules, 2023 - mdpi.com
Alzheimer's (AD) and Parkinson's diseases (PD) are multifactorial neurogenerative
disorders of the Central Nervous System causing severe cognitive and motor deficits in …

Identification and Characterization of Neuroprotective Properties of Thaumatin-like Protein 1a from Annurca Apple Flesh Polyphenol Extract

A D'Errico, R Nasso, A Di Maro, N Landi, A Chambery… - Nutrients, 2024 - mdpi.com
Background: Alzheimer's disease (AD) and Parkinson's disease (PD) are multifactorial
neurodegenerative disorders that are mostly treated with drugs inhibiting key enzymes of …

Annurca Apple Polyphenol Extract Affects Acetyl- Cholinesterase and Mono-Amine Oxidase In Vitro Enzyme Activity

R Nasso, V Pagliara, S D'Angelo, R Rullo, M Masullo… - Pharmaceuticals, 2021 - mdpi.com
In this study, we explored the ability of Annurca apple flesh polyphenol extract (AFPE) to
affect the activity of key enzymes involved in neurodegenerative disorders—in particular …

[HTML][HTML] MECP2 promotes the migration and invasion of gastric cancer cells by modulating the Notch1/c-Myc/mTOR signaling pathways by suppressing FBXW7 …

L Zhao, X Wang, J Yang, Q Jiang, J Zhang… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Methyl-CpG-binding protein 2 (MECP2), an epigenetic regulatory factor, promotes
the carcinogenesis and progression of a number of cancers. However, its role in the …

Inhibition of interleukin-6-induced matrix metalloproteinase-2 expression and invasive ability of lemon peel polyphenol extract in human primary colon cancer cells

V Pagliara, M De Rosa, P Di Donato, R Nasso… - Molecules, 2021 - mdpi.com
Among matrix metalloproteinases (MMPs), MMP-9/2 are key enzymes involved in the
proteolysis of extracellular matrices in the inflammatory process and in cancer. Since MMP …

[HTML][HTML] Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …