Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease

K Matsushita, SH Ballew, AYM Wang… - Nature Reviews …, 2022 - nature.com
Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

[HTML][HTML] The role of microbiota in infant health: from early life to adulthood

Y Yao, X Cai, Y Ye, F Wang, F Chen… - Frontiers in …, 2021 - frontiersin.org
From early life to adulthood, the microbiota play a crucial role in the health of the infant. The
microbiota in early life are not only a key regulator of infant health but also associated with …

[HTML][HTML] The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

Y Talmor-Barkan, N Bar, AA Shaul, N Shahaf… - Nature medicine, 2022 - nature.com
Complex diseases, such as coronary artery disease (CAD), are often multifactorial, caused
by multiple underlying pathological mechanisms. Here, to study the multifactorial nature of …

[HTML][HTML] The impact of CKD on uremic toxins and gut microbiota

J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

Cardiovascular disease in dialysis patients

M Cozzolino, M Mangano, A Stucchi… - Nephrology Dialysis …, 2018 - academic.oup.com
Cardiovascular disease (CVD) is a highly common complication and the first cause of death
in patients with end-stage renal disease (ESRD) on haemodialysis (HD). In this population …

Gut microbiota in cardiovascular health and disease

WHW Tang, T Kitai, SL Hazen - Circulation research, 2017 - Am Heart Assoc
Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …

Diet–microbiota interactions as moderators of human metabolism

JL Sonnenburg, F Bäckhed - Nature, 2016 - nature.com
It is widely accepted that obesity and associated metabolic diseases, including type 2
diabetes, are intimately linked to diet. However, the gut microbiota has also become a focus …

Gut microbiota, metabolites and host immunity

MG Rooks, WS Garrett - Nature reviews immunology, 2016 - nature.com
The microbiota—the collection of microorganisms that live within and on all mammals—
provides crucial signals for the development and function of the immune system. Increased …

Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

X Wang, S Yang, S Li, L Zhao, Y Hao, J Qin, L Zhang… - Gut, 2020 - gut.bmj.com
Objective Patients with renal failure suffer from symptoms caused by uraemic toxins,
possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is …