Personalized proteomics: the future of precision medicine
TT Duarte, CT Spencer - Proteomes, 2016 - mdpi.com
Medical diagnostics and treatment has advanced from a one size fits all science to treatment
of the patient as a unique individual. Currently, this is limited solely to genetic analysis …
of the patient as a unique individual. Currently, this is limited solely to genetic analysis …
Recent advances in robotic protein sample preparation for clinical analysis and other biomedical applications
Discovery of new protein biomarker candidates has become a major research goal in the
areas of clinical chemistry, analytical chemistry, and biomedicine. These important species …
areas of clinical chemistry, analytical chemistry, and biomedicine. These important species …
Mass spectrometry for identification, monitoring, and minimal residual disease detection of M-proteins
M Zajec, P Langerhorst, MM VanDuijn… - Clinical …, 2020 - academic.oup.com
Abstract Background Monoclonal gammopathies (MGs) are plasma cell disorders defined by
the clonal expansion of plasma cells, resulting in the characteristic excretion of a …
the clonal expansion of plasma cells, resulting in the characteristic excretion of a …
in-Facemask device for direct mass spectrometry analysis of human respiratory aerosols and environmental exposures via wearable continuous-flow adsorptive …
SH Cai, D Di, ZC Yuan, W Chen, B Hu - Analytical Chemistry, 2021 - ACS Publications
Facemasks are considered safe and wearable devices that cover the human mouth and
nose for filtering exhaled aerosols and inhaled environmental exposures; various chemical …
nose for filtering exhaled aerosols and inhaled environmental exposures; various chemical …
Mass Spectrometry–Based Proteogenomics: New Therapeutic Opportunities for Precision Medicine
SK Joshi, P Piehowski, T Liu… - Annual review of …, 2024 - annualreviews.org
Proteogenomics refers to the integration of comprehensive genomic, transcriptomic, and
proteomic measurements from the same samples with the goal of fully understanding the …
proteomic measurements from the same samples with the goal of fully understanding the …
Conjugating immunoassays to mass spectrometry: Solutions to contemporary challenges in clinical diagnostics
KG Stevens, TL Pukala - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Developments in immunoassays and mass spectrometry have independently influenced
diagnostic technology. However, both techniques possess unique strengths and limitations …
diagnostic technology. However, both techniques possess unique strengths and limitations …
Looking deeper into ocular surface health: an introduction to clinical tear proteomics analysis
J Nättinen, U Aapola, P Nukareddy… - Acta …, 2022 - Wiley Online Library
Ocular surface diseases are becoming more prevalent worldwide. Reasons for this include
the ongoing population ageing and increasing use of digital displays, although …
the ongoing population ageing and increasing use of digital displays, although …
The use of in-strip digestion for fast proteomic analysis on tear fluid from dry eye patients
Z Huang, CX Du, XD Pan - PLoS One, 2018 - journals.plos.org
Tear is an accessible fluid for exploring biomarkers of dry eye disease. This study describes
a fast proteomic method by LC-Q-orbitrap-MS analysis with in-strip digestion and …
a fast proteomic method by LC-Q-orbitrap-MS analysis with in-strip digestion and …
[HTML][HTML] Mass spectrometry in clinical glycomics: The path from biomarker identification to clinical implementation
Over the past decades, the genome and proteome have been widely explored for biomarker
discovery and personalized medicine. However, there is still a large need for improved …
discovery and personalized medicine. However, there is still a large need for improved …
Direct Monitoring of Fucosylated Glycopeptides of Alpha‐Fetoprotein in Human Serum for Early Hepatocellular Carcinoma by Liquid Chromatography–Tandem Mass …
Abstract Purpose: Alpha‐fetoprotein (AFP) is a widely used serological marker that is
associated with hepatocellular carcinoma (HCC). Although the level of AFP is increased in …
associated with hepatocellular carcinoma (HCC). Although the level of AFP is increased in …