Indole alkaloids are widely distributed in nature and have been particularly studied because
of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and …

Evodia rutaecarpa, the near-ripe fruit of Euodia rutaecarpa (Juss.) Benth, Euodia rutaecarpa
(Juss.) Benth. var. officinalis (Dode) Huang, or Euodia rutaecarpa (Juss.) Benth. var …

Abstract Di (2-ethylhexyl) phthalate (DEHP) is a neuroendocrine disruptor that can cause
multi-tissue organ damage by inducing oxidative stress. Evodiamine (EVO) is an indole …

Silicosis is a common and ultimately fatal occupational disease, yet the limited therapeutic
option remains the major clinical challenge. Apelin, an endogenous ligand of the G-protein …

Loss of FXR, one of bile acid receptors, enlarged livers. Yes‐associated protein 1 (YAP1), a
dominant oncogene, promotes hepatocellular carcinoma (HCC). However, the relationship …

Aloesone is a major metabolic compound in Aloe vera, which has been widely used as a
food source and therapeutic agent in several countries. Our recent study demonstrated that …

Background Acute respiratory distress syndrome (ARDS) is a serious life threatening clinical
critical illness. ARDS-related pulmonary fibrosis is a common complication of ARDS. The …

Vascular disease is a common problem with high mortality all over the world. Apelin-13, a
key subtype of apelin, takes part in many physiological and pathological responses via …

Cellular senescence plays a very important role in the ageing of organisms and age-related
diseases that increase with age, a process that involves physiological, structural …

Degradation of extracellular matrix (ECM), reactive oxygen species (ROS) production, and
inflammation are critical players in the pathogenesis of intervertebral disc degeneration …