Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

Ethnopharmacological relevance The lateral root of Aconitum carmichaelii Debx is known as
Fuzi in Chinese. It is traditionally valued and used for dispelling cold, relieving pain effects …

Diabetes is a disorder of glucose metabolism, and over 90% are type 2 diabetes. Diabetic
cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by …

Excessive generation of mitochondrial reactive oxygen species (ROS) is considered to be
initiating event in the development of diabetic nephropathy (DN). Mitochondrial biosynthesis …

Ethnopharmacological relevance The lateral root of Aconitum carmichaelii Debeaux.(also
known as Fuzi in Chinese) is a toxic Chinese medicine but widely used in clinical practice …

Aconitine (AC) is well‐known as the main toxic ingredient and active compound of Aconitum
species, of which several aconites are essential herbal medicines of Traditional Chinese …

About 50% of the diabetic patients worldwide suffer from Diabetic peripheral neuropathy
(DPN) which is characterized by chronic pain and loss of sensation, frequent foot …

Aconitum carmichaeli Debx.-derived herbal medicine has been used for anti-inflammation
and anti-arrhythmia purpose for more than two thousand years. It is processed into …

Backgrounds: Salsolinol (SAL), a plant-based isoquinoline alkaloid, was initially isolated
from Aconiti Lateralis Radix Praeparata (ALRP) and identified as the active cardiotonic …

Background. Myocardial infarction (MI) is a severe clinical condition caused by decreased or
complete cessation of blood flow to a portion of the myocardium. Aconite, the lateral roots of …