The Bohr effect of haemoglobin in vertebrates: an example of molecular adaptation to different physiological requirements

B Giardina, D Mosca… - Acta physiologica …, 2004 - Wiley Online Library
The Bohr effect, ie the pH dependence of the oxygen affinity of haemoglobins (Hbs) from a
variety of vertebrates, and its modulation by temperature and other heterotropic effectors has …

Oxygen transport in extreme environments

G di Prisco, SG Condo, M Tamburrini… - Trends in biochemical …, 1991 - Elsevier
Evolution has adopted different strategies to solve the problem of transporting oxygen to
respiring tissues, according to needs dictated by the environment. A thermodynamic …

Convergent molecular evolution of thermogenesis and circadian rhythm in Arctic ruminants

M Li, X Li, Z Wu, G Zhang, N Wang… - … of the Royal …, 2023 - royalsocietypublishing.org
The muskox and reindeer are the only ruminants that have evolved to survive in harsh Arctic
environments. However, the genetic basis of this Arctic adaptation remains largely unclear …

High affinity and temperature sensitivity of blood oxygen binding in Pangasianodon hypophthalmus due to lack of chloride-hemoglobin allosteric interaction

C Damsgaard, LM Phuong… - American Journal …, 2015 - journals.physiology.org
Air-breathing fishes represent interesting organisms in terms of understanding the
physiological changes associated with the terrestrialization of vertebrates, and, further, are …

Hemoglobin function under extreme life conditions

ME Clementi, SG Condo, M Castagnola… - European Journal of …, 1994 - Wiley Online Library
Considering the variety of species that depend on hemoglobin for oxygen transport, these
molecules must execute their primary function under extreme environmental conditions …

From the arctic to fetal life: physiological importance and structural basis of an additional chloride-binding site in haemoglobin

MC De Rosa, M Castagnola, C Bertonati… - Biochemical …, 2004 - portlandpress.com
Haemoglobins from mammals of sub-Arctic and Arctic species, as well as fetal human Hb,
are all characterized by a significantly lower Δ H of oxygenation compared with the majority …

A comparative study of the temperature dependence of the oxygen‐binding properties of mammalian hemoglobins

M Coletta, ME Clementi, P Ascenzi… - European journal of …, 1992 - Wiley Online Library
The effect of temperature on the oxygen‐binding properties of hemoglobin (Hb) from
ruminants, such as ox, reindeer, musk ox, mouflon and egyptian water buffalo is compared …

The basic defect in cystic fibrosis

JH Widdicombe, JJ Wine - Trends in biochemical sciences, 1991 - Elsevier
Recent evidence strongly suggests that the cystic fibrosis gene product (CFTR) is a Cl−
channel. Its properties, however, differ from those of a 30–50 pS outwardly rectifying channel …

Molecular basis of low‐temperature sensitivity in pig hemoglobins

SG Condó, M Corda, MT Sanna… - European journal of …, 1992 - Wiley Online Library
It has been generally assumed that mammals have blood with a greater temperature
sensitivity than ectothermic organisms. Recent results have shown that in some species of …

Arctic life adaptation--III. The function of whale (Balaenoptera acutorostrata) hemoglobin.

O Brix, SG Condó, G Lazzarino… - … and physiology. B …, 1989 - europepmc.org
1. The oxygen binding properties of the hemoglobin from the Lesser Rorqual, Balaenoptera
acutorostrata, has been investigated with respect to the possible effects of organic …