Comparison of microgravity analogs to spaceflight in studies of plant growth and development
Life on Earth has evolved under the influence of gravity. This force has played an important
role in shaping development and morphology from the molecular level to the whole …
role in shaping development and morphology from the molecular level to the whole …
Factors implicating the validity and interpretation of mechanobiology studies in simulated microgravity environments
C Poon - Engineering Reports, 2020 - Wiley Online Library
Simulated microgravity (s‐μg) devices provide unique conditions for elucidating the effects
of gravitational unloading on biological processes and are increasingly being applied for …
of gravitational unloading on biological processes and are increasingly being applied for …
Novel, Moon and Mars, partial gravity simulation paradigms and their effects on the balance between cell growth and cell proliferation during early plant development
Abstract Clinostats and Random Positioning Machine (RPM) are used to simulate
microgravity, but, for space exploration, we need to know the response of living systems to …
microgravity, but, for space exploration, we need to know the response of living systems to …
Dexamethasone selectively inhibits detachment of metastatic thyroid cancer cells during random positioning
D Melnik, JL Cortés-Sánchez, V Sandt, S Kahlert… - Cancers, 2023 - mdpi.com
Simple Summary Metastasis is the most dangerous feature of advanced cancers. In vitro
models of this process could help us to study and understand mechanisms that are not …
models of this process could help us to study and understand mechanisms that are not …
Gene-environmental influence of space and microgravity on red blood cells with sickle cell disease
NE Igbineweka, JJWA van Loon - NPJ Genomic Medicine, 2024 - nature.com
A fundamental question in human biology and for hematological disease is how do complex
gene-environment interactions lead to individual disease outcome? This is no less the case …
gene-environment interactions lead to individual disease outcome? This is no less the case …
Simulated microgravity inhibits the proliferation of chang liver cells by attenuation of the major cell cycle regulators and cytoskeletal proteins
Simulated microgravity (SMG) induced the changes in cell proliferation and cytoskeleton
organization, which plays an important factor in various cellular processes. The inhibition in …
organization, which plays an important factor in various cellular processes. The inhibition in …
[HTML][HTML] Differential transcriptional profile through cell cycle progression in Arabidopsis cultures under simulated microgravity
Plant cell proliferation is affected by microgravity during spaceflight, but involved molecular
mechanisms, key for space agronomy goals, remain unclear. To investigate transcriptomic …
mechanisms, key for space agronomy goals, remain unclear. To investigate transcriptomic …
Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine
JL Cortés-Sánchez, D Melnik, V Sandt, S Kahlert… - Cells, 2023 - mdpi.com
In preparing space and microgravity experiments, the utilization of ground-based facilities is
common for initial experiments and feasibility studies. One approach to simulating …
common for initial experiments and feasibility studies. One approach to simulating …
Morphological Changes of 3T3 Cells under Simulated Microgravity
MT Tran, CNQ Ho, SN Hoang, CC Doan, MT Nguyen… - Cells, 2024 - mdpi.com
Background: Cells are sensitive to changes in gravity, especially the cytoskeletal structures
that determine cell morphology. The aim of this study was to assess the effects of simulated …
that determine cell morphology. The aim of this study was to assess the effects of simulated …
Omics Studies of Tumor Cells under Microgravity Conditions
Cancer is defined as a group of diseases characterized by abnormal cell growth, expansion,
and progression with metastasis. Various signaling pathways are involved in its …
and progression with metastasis. Various signaling pathways are involved in its …