Glioblastoma multiforme (GBM), an aggressive tumor that typically exhibits treatment failure
with high mortality rates, is associated with the presence of cancer stem cells (CSCs) within …

Glioblastoma is the most common and most aggressive primary brain malignancy. The
current initial standard of care consists of maximal safe surgical resection followed by radical …

Glioblastomas (GBMs) are highly vascular and lethal brain tumors that display cellular
hierarchies containing self-renewing tumorigenic glioma stem cells (GSCs). Because GSCs …

The role of autophagy in cancer onset and progression appears still controversial. On one
hand, autophagy allows cancer cell to survive in unfavorable environmental conditions, on …

Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels of which are
thought to arise by sprouting of pre-existing brain capillaries. The recent demonstration that …

Background Glioblastoma (GBM) is the most common and aggressive primary malignant
brain tumor in adults, characterized by a poor prognosis mainly due to recurrence and …

Previously, we described the safety and therapeutic potential of neurospheres (NSs) derived
from a human induced pluripotent stem cell (iPSC) clone, 201B7, in a spinal cord injury …

Glioblastoma is one of the most angiogenic human tumours and endothelial proliferation is a
hallmark of the disease. A better understanding of glioblastoma vasculature is needed to …

Metastasis is the major cause of cancer-related deaths. Invasive primary cancers often
metastasize after circulating tumor cells (CTCs) enter the bloodstream or lymph node to …

The human genome encodes a variety of poorly understood RNA species that remain
challenging to identify using existing genomic tools. We developed chromatin run-on and …