Bicelles as model membranes for solid‐and solution‐state NMR studies of membrane peptides and proteins

I Marcotte, M Auger - Concepts in Magnetic Resonance Part A …, 2005 - Wiley Online Library
Bicelles are an attractive membrane mimetic system because of their planar surface and
lipid composition, which resemble biological membranes. In addition, their orientation and …

When detergent meets bilayer: birth and coming of age of lipid bicelles

UHN Dürr, R Soong, A Ramamoorthy - Progress in nuclear magnetic …, 2013 - Elsevier
► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

Rapid cold-hardening increases membrane fluidity and cold tolerance of insect cells

RE Lee Jr, K Damodaran, SX Yi, GA Lorigan - Cryobiology, 2006 - Elsevier
The rapid cold-hardening (RCH) response not only confers dramatic protection against cold-
shock (non-freezing) injury, but also “instantaneously” enhances organismal performance …

Probing the interaction of polyphenols with lipid bilayers by solid-state NMR spectroscopy

X Yu, S Chu, AE Hagerman… - Journal of agricultural and …, 2011 - ACS Publications
Polyphenols are bioactive natural products that appear to act against a wide range of
pathologies. Mechanisms of activity have not been established, but recent studies have …

Investigating structural changes in the lipid bilayer upon insertion of the transmembrane domain of the membrane-bound protein phospholamban utilizing 31P and 2H …

PC Dave, EK Tiburu, K Damodaran, GA Lorigan - Biophysical journal, 2004 - cell.com
Abstract Phospholamban (PLB) is a 52-amino acid integral membrane protein that regulates
the flow of Ca 2+ ions in cardiac muscle cells. In the present study, the transmembrane …

A 2H solid-state NMR spectroscopic investigation of biomimetic bicelles containing cholesterol and polyunsaturated phosphatidylcholine

RE Minto, PR Adhikari, GA Lorigan - Chemistry and physics of lipids, 2004 - Elsevier
Deuterium solid-state NMR spectroscopy was used to qualitatively study the effects of both 1-
palmitoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine (PLiPC) and cholesterol on …

Solid-state nuclear magnetic resonance relaxation studies of the interaction mechanism of antimicrobial peptides with phospholipid bilayer membranes

JX Lu, K Damodaran, J Blazyk, GA Lorigan - Biochemistry, 2005 - ACS Publications
An 18-residue peptide, KWGAKIKIGAKIKIGAKI-NH2 was designed to form amphiphilic β-
sheet structures when bound to lipid bilayers. The peptide possesses high antimicrobial …

The effects of cholesterol on magnetically aligned phospholipid bilayers: a solid-state NMR and EPR spectroscopy study

JX Lu, MA Caporini, GA Lorigan - Journal of magnetic resonance, 2004 - Elsevier
This paper presents the first time that both solid-state NMR spectroscopy and EPR
spectroscopy are used to study the effects of cholesterol on magnetically aligned …

Solid-state NMR spectroscopic studies of an integral membrane protein inserted into aligned phospholipid bilayer nanotube arrays

GA Lorigan, PC Dave, EK Tiburu… - Journal of the …, 2004 - ACS Publications
This communication demonstrates for the first time that solid-state NMR spectroscopic
studies can be used to investigate aligned phospholipid bilayer nanotube arrays. Also, an …

Biopharmaceutical trials of a dosage form, which contain methionine and turmeric extract (Curcuma longa L.)

OA Gizinger, AA Khisamova - Drug development & registration, 2021 - pharmjournal.ru
Introduction. The presence of biologically active substances in the extract from the roots of
turmeric extract (Curcuma longa L.) makes it reasonable and makes it possible to predict …