Tractography methods and findings in brain tumors and traumatic brain injury
White matter fiber tracking using diffusion magnetic resonance imaging (dMRI) provides a
noninvasive approach to map brain connections, but improving anatomical accuracy has …
noninvasive approach to map brain connections, but improving anatomical accuracy has …
Translational models of mild traumatic brain injury tissue biomechanics
Traumatic brain injury (TBI) is a global health concern. Mild TBI (mTBI) which accounts for
the majority of TBI cases, is hard to detect since often the imaging is normal but can still …
the majority of TBI cases, is hard to detect since often the imaging is normal but can still …
An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …
develop protection systems. The generation of anatomically accurate and subject-specific …
Development of a second-order system for rapid estimation of maximum brain strain
Diffuse brain injuries are assessed with deformation-based criteria that utilize metrics based
on rotational head kinematics to estimate brain injury severity. Although numerous metrics …
on rotational head kinematics to estimate brain injury severity. Although numerous metrics …
Instantaneous whole-brain strain estimation in dynamic head impact
Head injury models are notoriously time consuming and resource demanding in simulations,
which prevents routine application. Here, we extend a convolutional neural network (CNN) …
which prevents routine application. Here, we extend a convolutional neural network (CNN) …
Embedded axonal fiber tracts improve finite element model predictions of traumatic brain injury
With the growing rate of traumatic brain injury (TBI), there is an increasing interest in
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …
A reanalysis of football impact reconstructions for head kinematics and finite element modeling
Background Head kinematics generated by laboratory reconstructions of professional
football helmet impacts have been applied to computational models to study the …
football helmet impacts have been applied to computational models to study the …
Convolutional neural network for efficient estimation of regional brain strains
Head injury models are important tools to study concussion biomechanics but are
impractical for real-world use because they are too slow. Here, we develop a convolutional …
impractical for real-world use because they are too slow. Here, we develop a convolutional …
Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …
there is an ongoing debate on what experimental data are suitable for model validation …
White matter anisotropy for impact simulation and response sampling in traumatic brain injury
Advanced neuroimaging provides new opportunities to enhance head injury models,
including the incorporation of white matter (WM) structural anisotropy. Information from high …
including the incorporation of white matter (WM) structural anisotropy. Information from high …