Tractography methods and findings in brain tumors and traumatic brain injury

FC Yeh, A Irimia, DC de Almeida Bastos, AJ Golby - Neuroimage, 2021 - Elsevier
White matter fiber tracking using diffusion magnetic resonance imaging (dMRI) provides a
noninvasive approach to map brain connections, but improving anatomical accuracy has …

Translational models of mild traumatic brain injury tissue biomechanics

X Zhan, A Oeur, Y Liu, MM Zeineh, GA Grant… - Current Opinion in …, 2022 - Elsevier
Traumatic brain injury (TBI) is a global health concern. Mild TBI (mTBI) which accounts for
the majority of TBI cases, is hard to detect since often the imaging is normal but can still …

An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain

X Li, Z Zhou, S Kleiven - Biomechanics and modeling in mechanobiology, 2021 - Springer
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …

Development of a second-order system for rapid estimation of maximum brain strain

LF Gabler, JR Crandall, MB Panzer - Annals of biomedical engineering, 2019 - Springer
Diffuse brain injuries are assessed with deformation-based criteria that utilize metrics based
on rotational head kinematics to estimate brain injury severity. Although numerous metrics …

Instantaneous whole-brain strain estimation in dynamic head impact

K Ghazi, S Wu, W Zhao, S Ji - Journal of Neurotrauma, 2021 - liebertpub.com
Head injury models are notoriously time consuming and resource demanding in simulations,
which prevents routine application. Here, we extend a convolutional neural network (CNN) …

Embedded axonal fiber tracts improve finite element model predictions of traumatic brain injury

M Hajiaghamemar, T Wu, MB Panzer… - … and modeling in …, 2020 - Springer
With the growing rate of traumatic brain injury (TBI), there is an increasing interest in
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …

A reanalysis of football impact reconstructions for head kinematics and finite element modeling

EJ Sanchez, LF Gabler, AB Good, JR Funk… - Clinical …, 2019 - Elsevier
Background Head kinematics generated by laboratory reconstructions of professional
football helmet impacts have been applied to computational models to study the …

Convolutional neural network for efficient estimation of regional brain strains

S Wu, W Zhao, K Ghazi, S Ji - Scientific reports, 2019 - nature.com
Head injury models are important tools to study concussion biomechanics but are
impractical for real-world use because they are too slow. Here, we develop a convolutional …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …

White matter anisotropy for impact simulation and response sampling in traumatic brain injury

W Zhao, S Ji - Journal of neurotrauma, 2019 - liebertpub.com
Advanced neuroimaging provides new opportunities to enhance head injury models,
including the incorporation of white matter (WM) structural anisotropy. Information from high …